Publications by authors named "Myrto Astriti"
People living with HIV-HCV co-infection comprise a target group for HCV-micro-elimination. We conducted an HCV cascade of care (CoC) for HIV-HCV co-infected individuals living in Greece and investigated factors associated with different HCV-CoC stages. We analyzed data from 1213 participants from the Athens Multicenter AIDS Cohort Study.
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- Researchers studied how different immune endotypes affect responses to anakinra treatment in patients with severe pneumonia caused by COVID-19 during the SAVE-MORE trial.
- The study found that many patients transitioned between immune endotypes during treatment, with anakinra helping those with the adaptive endotype to maintain better outcomes.
- Anakinra also reduced the risk of severe respiratory failure in patients with a coagulopathic endotype compared to placebo, indicating its potential benefits in managing sepsis-related conditions.
Article Synopsis
- The study aimed to evaluate a blood test that measures MxA and CRP levels to differentiate between viral and bacterial respiratory infections in adults.
- A total of 537 patients were analyzed, leading to the development of a diagnostic equation with high sensitivity for bacterial infections (91.6%).
- The findings suggest that using MxA and CRP measurements can effectively identify the type of respiratory infection, helping guide appropriate treatment.
A Rare Convergence: Adult-Onset Langerhans Cell Histiocytosis and HIV Infection.
Eur J Case Rep Intern Med
November 2023
Unlabelled: While primarily described in children, adult-onset Langerhans cell histiocytosis (LCH) has been reported, albeit infrequently. In the present scenario, we unveil a unique case of adult-onset LCH in an HIV-infected individual. After the diagnosis was made, the patient was successfully treated and demonstrated total disease remission.
View Article and Find Full Text PDFOur aim was to estimate the date of the origin and the transmission rates of the major local clusters of subtypes A1 and B in Greece. Phylodynamic analyses were conducted in 14 subtype A1 and 31 subtype B clusters. The earliest dates of origin for subtypes A1 and B were in 1982.
View Article and Find Full Text PDFBlack widow spider is endemic in the Mediterranean area and although envenomations are rare, may occasionally lead to death. We present a case of a 64-year-old female developing a rare variant of takotsubo, stress-induced, cardiomyopathy after a spider bite. This resulted in acute heart failure within 24 hours of the bite.
View Article and Find Full Text PDFA case is presented of intestinal schistosomiasis due to both Schistosoma intercalatum and Schistosoma mansoni in a 30-year-old man from Senegal with discussion of diagnostic approach, species identification and determination of the effect of treatment. The patient was admitted to hospital for investigation of renal failure, arterial hypertension and hypereosinophilia. Repeated stool examinations for ova and parasites were negative.
View Article and Find Full Text PDFWe describe the case of a patient infected with HIV and a concomitant HHV-6 encephalitis. The patient experienced virological failure following cidofovir treatment. RT-PCR was used both for early diagnosis and follow-up.
View Article and Find Full Text PDFObjective: To evaluate the efficacy and tolerability of indinavir/ritonavir (IDV/RTV) 400/100 mg twice daily in combination with two nucleoside reverse transcriptase inhibitors in antiretroviral-naive patients.
Design And Methods: Antiviral therapy-naive patients with plasma HIV-1 RNA > 5000 copies/ml were enrolled in this pilot, single-arm study. CD4 cell count and viral load were evaluated at weeks (W) 4, 12, 24 and every 3 months until W48.