Publications by authors named "Myrthe Willems"

Article Synopsis
  • Serum neurofilament light (sNfL) serves as a biomarker for neuro-axonal damage in multiple sclerosis (MS) but its clinical usage is still limited; this study assessed how its implementation affects clinical decisions at the MS Center Amsterdam.
  • Over the study period (August 2021-December 2022), sNfL was evaluated in various contexts, with a notable change in clinical decisions in 19.3% of cases, especially when assessing new symptoms or when higher sNfL levels were present.
  • The findings suggest that integrating sNfL into clinical practice improved decision-making certainty and potentially adjusted expectations regarding MRI activity, indicating its potential value in patient care while calling for further research
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Sudden changes in behaviour and concentration problems can be caused by non-convulsive status epilepticus. This generalised form of epilepsy can be easily missed as a diagnosis. In this case report series we describe three adolescent boys (13, 14 and 17 years old respectively) presenting with behavioural disturbances caused by idiopathic non-convulsive status epilepticus.

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