Zika without symptoms in returning travellers: What are the implications?

Against the background of the emergence and rapid spread of Zika virus (ZIKV) in the Americas, we report the case of an afebrile ZIKV infection in a traveller returning from Central America to highlight relevant clinical and diagnostic aspects. ZIKV should be considered in the differential diagnosis of patients with clinical symptoms suggestive of dengue or chikungunya fever. Given the frequent subfebril and afebrile manifestations of ZIKV infections, we propose abstaining from the term "Zika fever (ZF)" in favour of "Zika virus disease (ZVD)".