Publications by authors named "Mylene Bertrand"
Background: Chronic rhinosinusitis with nasal polyposis (CRSwNP) affects a significant number of asthmatic patients and is notably associated with a more difficult-to-control asthma and marked inflammation. We need more studies on this specific asthma phenotype and its possible subphenotypes, in order to better individualize treatments.
Aim: The aim of this study is to identify and characterize subphenotypes of asthma patients with CRSwNP using clinical, physiological and inflammatory variables.
Article Synopsis
- * Key predictors for this suboptimal response include reliance on daily prednisone, having sinus issues, and being diagnosed with late-onset asthma.
- * Patients showing signs of worsening asthma often had signs of autoimmune activity, as indicated by specific biomarkers in their sputum, suggesting a more complex underlying condition may affect treatment efficacy.
Background: Induced sputum (IS) analysis is a noninvasive, valid, and reproducible method for evaluating airway inflammation. It has been suggested that freezing of IS samples in order to delay analysis is feasible. However, the optimal conditions for preservation of IS samples have not been determined.
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