Publications by authors named "Mykola P Kopytsya"

Objective: The aim: To estimate the role of macrophage migration inhibitory factor and soluble ST2 in predicting the left ventricle remodeling six months after ST-segment elevation myocardial infarction.

Patients And Methods: Materials and methods: The study involved 134 ST-segment elevation myocardial infarction patients. Occurrence of post-percutaneous coronary (PCI) intervention epicardial blood flow of TIMI <3 or myocardial blush grade 0-1 along with ST resolution <70% within 2 hours after PCI was qualified as the no-reflow condition.

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Objective: Aim of our study was to determine the role of the clinical and biochemical markers in predicting the outcomes at one year in patients with STEMI who have undergone primary PCI.

Patients And Methods: Materials and methods: The study included 165 patients admitted with STEMI within 12 hours of the onset of symptoms be¬tween January 2020 and August 2021. All patients underwent primary PCI according to the guidelines, followed by standard examination and treatment at the hospital.

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Article Synopsis
  • Acute coronary syndrome (ACS) is a significant health issue globally, leading to high mortality rates and disability among patients, with GDF-15 emerging as a critical biomarker in cardiovascular disease research.
  • A study involving 70 ACS patients found a strong correlation between elevated GDF-15 levels and adverse outcomes within five years, with a specific GDF-15 threshold predicting complications with reasonable accuracy.
  • The findings suggest that measuring GDF-15 within the first 24 hours post-ACS can help identify patients at higher risk of poor long-term outcomes.
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Objective: The aim: The aim is to study the effect of β-ABs in patients with LT3 S on the course of HF.

Patients And Methods: Materials and methods: 354 patients with HF on a background of post-infarction cardiosclerosis were included in the 2-yeared follow-up study. LT3 S was diagnosed at 89 (25.

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To investigate associations between subclinical distress and 6-month clinical outcomes after ST-segment elevation myocardial infarction (STEMI). The case-control study involved 144 STEMI patients (72 STEMI having subclinical emotional disturbances were included to the case group and 72 STEMI individuals matched with age, sex and cardiovascular risk factors were enrolled to the control group). The primary end point was the combination of 6-month events including CV death, recurrent angina, newly diagnosed heart failure and re-hospitalization.

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Unlabelled: The course of heart failure (HF) and its progression is associated with comorbidities, genetic factors and a dynamics of a number of biomarkers. The low triiodothyronine syndrome (LT3S) is observed in some patients with HF. Extremely little data are available in the literature regarding the effect of β-adrenoreceptors (β-AR) genes polymorphisms on the development of LT3S and many contradictory results about their association with HF course.

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