CHANGES IN THE SERUM LEVEL OF LEPTIN AND TRANSFORMING GROWTH FACTOR-Β1 IN PATIENTS WITH ARTERIAL HYPERTENSION ON A BACKGROUND OF ABDOMINAL OBESITY.

Objective: The aim: Study of the levels of leptin and the growth modulator TGF-β1 in the blood serum of patients with hypertension, which occurs on the background of AO and without it.

Patients And Methods: Materials and methods: Carbohydrate metabolism was studied by the enzymatic method, the level of insulin in the blood (by the enzyme immunoassay method), the oral glucose tolerance test and the calculation of the NOMA index.

Results: Results: The data obtained in the work indicate a significant role of leptin in the formation of hypertension itself and the development of obesity, carbohydrate and lipid metabolism disorders.