Publications by authors named "My-Linh Ma"
Background: The use of quantitative sensory testing (QST) in multicenter studies has been quite limited, due in part to lack of standardized procedures among centers.
Aim: The aim of this study was to assess the application of the capsaicin pain model as a surrogate experimental human model of neuropathic pain in different centers and verify the variation in reports of QST measures across centers.
Methods: A multicenter study conducted by the Quebec Pain Research Network in six laboratories allowed the evaluation of nine QST parameters in 60 healthy subjects treated with topical capsaicin to model unilateral pain and allodynia.
Article Synopsis
- RSV is a leading cause of pneumonia and bronchiolitis in children, with low mortality in healthy kids but significantly higher in those with underlying health issues.
- A study from 2003–2013 identified 79 deaths related to RSV in Canadian pediatric centers, finding that 40.5% were primarily attributed to RSV and nearly 50% of patients were male, with a median age of death at 11 months.
- Over a third of the deaths were linked to healthcare-associated RSV infections, emphasizing the need for targeted prevention strategies for vulnerable groups, including better infection control and vaccination efforts.
Conditioned pain modulation (CPM) paradigms have been used in various studies with healthy and non-healthy adult populations in an attempt to elucidate the mechanisms of pain processing. However, only a few studies so far have applied CPM in pediatric populations. Studies finding associations with chronic pain conditions suggest that deficiencies in underlying descending pain pathways may play an important role in the development and persistence of pain early in life.
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