Publications by authors named "Mv Senat"

Article Synopsis
  • This study investigated the incidence and risk factors for complete uterine rupture among women attempting vaginal birth after cesarean delivery (VBAC) over a 16-year period in France.
  • Out of 48,124 patients with a prior cesarean section, 65.8% attempted a VBAC, with a uterine rupture rate of 0.63%.
  • Key findings indicated that prior vaginal delivery decreased the risk of uterine rupture, while labor induction increased it; additionally, specific factors during spontaneous labor, like a low Bishop score and an arrest of cervical dilation, also heightened the risk.
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NAUSEA AND VOMITING IN PREGNANCY. Nausea and vomiting during pregnancy are common symptoms experienced by pregnant women. In more severe cases, known as hyperemesis gravidarum, these symptoms can become a pathological condition that can lead to significant complications in both the short and long term.

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Introduction: The use of different growth charts can lead to confusion in discussions between professionals. There are obstetric charts (of fetal growth) and neonatal charts (of measurements at birth and of postnatal growth). These charts can be descriptive (derived from an unselected population) or prescriptive (derived from of a population at low risk and with optimal conditions for growth).

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Objectives: The objective of our study was to evaluate the long-term outcome of children born from a pregnancy complicated by idiopathic polyhydramnios. The secondary objective was to investigate factors associated with adverse outcomes.

Methods: We conducted a retrospective study in two prenatal diagnosis centers between January 1, 2009 and December 31, 2020.

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Introduction: Prenatal investigations are usually performed to diagnose severe or associated forms of hypospadias. However, the value of this workup and the correlation with the postnatal diagnosis and follow-up have not been studied in the literature. The aims of the study were to describe postnatal outcomes.

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Objective: To assess which fetal growth charts best describe intrauterine growth in France defined as the ability to classify 10% of fetuses below the 10th percentile (small for gestational age [SGA]) and above the 90th percentile (large for gestational age [LGA]) in the second and third trimesters.

Methods: We analyzed five studies on fetal ultrasound measurements using three French data sources. Two studies used second and third trimester ultrasound data from a nationwide birth cohort in 2011 (the ELFE study, N = 13 197 and N = 7747); one study used third trimester ultrasound data from on a nationwide cross-sectional study (the 2016 French National Perinatal Survey, N = 9940); and the last two studies were from the "Flash study" 2014 which prospectively collected ultrasound data from routine visits in the second and third trimesters (N = 4858 and N = 3522).

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Article Synopsis
  • The study aimed to find ways to lower maternal and neonatal health issues linked to preeclampsia by reviewing literature and assessing the quality of evidence using the GRADE® method and PICO format.* -
  • The findings indicated that while encouraging physical activity during pregnancy is strongly recommended to decrease preeclampsia risk, broader definitions for preeclampsia and early screening with aspirin are not recommended due to low levels of evidence.* -
  • A consensus was reached among reviewers on all evaluated questions, but for women with preexisting health conditions, the evidence was insufficient to determine the effectiveness of aspirin in reducing risks associated with preeclampsia.*
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Objective: To identify strategies for reducing neonatal and maternal morbidity associated with intrahepatic cholestasis pregnancy (ICP).

Material And Methods: The quality of evidence of the literature was assessed following the GRADE methodology with questions formulated in the PICO format (Patients, Intervention, Comparison, Outcome) and outcomes defined a priori and classified according to their importance. An extensive bibliographic search was performed on PubMed, Cochrane, EMBASE and Google Scholar databases.

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Background: Incontinence occurs frequently in the postpartum period. Several theoretical pathophysiological models may underlie the hypothesis that different types of management of the active phase of the second stage of labor have different effects on pelvic floor muscles and thus perhaps affect urinary and anal continence.

Objective: This study aimed to evaluate the impact of "moderate pushing" on the occurrence of urinary or anal incontinence compared with "intensive pushing," and to determine the factors associated with incontinence at 6 months postpartum.

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Importance: Bacterial vaginosis (BV) is a well-known risk factor for preterm birth. Molecular diagnosis of BV is now available. Its impact in the screening and treatment of BV during pregnancy on preterm births has not been evaluated to date.

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Article Synopsis
  • The study investigates the effects of intrauterine balloon tamponade when used along with second-line uterotonics versus after the failure of second-line treatment in managing severe postpartum hemorrhage for women who had vaginal deliveries.
  • Conducted across 18 hospitals with 403 participants, it focuses on women with postpartum hemorrhage that did not respond to first-line treatment (oxytocin) and required additional intervention.
  • The primary outcome measured was the need for blood transfusions or excessive blood loss, with secondary outcomes including the frequency of significant blood loss, transfusions, invasive procedures, and ICU transfers.
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Objective: To identify procedures to reduce maternal morbidity during cesarean.

Material And Methods: The quality of evidence of the literature was assessed following the GRADE® method with questions formulated in the PICO format (Patients, Intervention, Comparison, Outcome) and outcomes defined a priori and classified according to their importance. An extensive bibliographic search was performed on PubMed, Cochrane and EMBASE databases.

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Objective: To determine the management of patients with 1st trimester nausea and vomiting and hyperemesis gravidarum.

Methods: A panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds.

Results: Hyperemesis gravidarum is distinguished from nausea and vomiting during pregnancy by weight loss≥5 % or signs of dehydration or a PUQE score≥7.

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Article Synopsis
  • The study examined the effects of "moderate" vs "intensive" pushing during the second stage of labor on neonatal health outcomes.
  • The research involved 1710 first-time mothers and compared outcomes between two groups: one with moderated pushing and another with intensive pushing, assessing factors like neonatal morbidity and mode of delivery.
  • Results showed that while the neonatal morbidity was slightly lower in the moderate group (18.9%) compared to the intensive group (20.6%), those in the moderate group pushed longer, averaging 38.8 minutes compared to 28.6 minutes for the intensive group.
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Background: Congenital portosystemic shunts (CPSS) are rare vascular malformations associated with the risk of life-threatening systemic conditions, which remain underdiagnosed and often are identified after considerable diagnostic delay. CPSS are characterized by multiple signs and symptoms, often masquerading as other conditions, progressing over time if the shunt remains patent. Which patients will benefit from shunt closure remains to be clarified, as does the timing and method of closure.

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Article Synopsis
  • Macrosomia (large birth weight) in babies born to diabetic mothers can lead to neonatal hypoglycemia, especially in cases of asymmetric macrosomia.
  • This research analyzed data from 890 pregnant women with gestational diabetes to find the link between baby weight and the risk of low blood sugar after birth.
  • Results showed that extreme birthweight or weight-length ratios significantly increased the odds of neonatal hypoglycemia, indicating that both very large and very small babies need close monitoring.
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Objective: To recommend the most appropriate biometric charts for the detection of antenatal growth abnormalities and postnatal growth surveillance.

Methods: Elaboration of specific questions and selection of experts by the organizing committee to answer these questions; analysis of the literature by experts and drafting conclusions by assigning a recommendation (strong or weak) and a quality of evidence (high, moderate, low, very low) and for each question; all these recommendations have been subject to multidisciplinary external review (obstetrician gynecologists, pediatricians). The objective for the reviewers was to verify the completeness of the literature review, to verify the levels of evidence established and the consistency and applicability of the resulting recommendations.

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Article Synopsis
  • Tranexamic acid (TXA) after cesarean delivery may reduce blood loss and transfusions, but it doesn’t significantly help with other hemorrhage-related issues, making its routine use uncertain.
  • The study aimed to see if TXA is effective in preventing blood loss specifically for women with multiple pregnancies undergoing cesarean deliveries.
  • Results showed no significant difference in blood loss between women receiving TXA and those on placebo, indicating that TXA may not be beneficial in this high-risk group.
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Objective: To assess survival to discharge without severe neonatal morbidity by planned mode of delivery for twins born before 32 weeks of gestation.

Methods: The JUMODA (JUmeaux MODe d'Accouchement) study was a French national prospective, population-based, cohort study of twin deliveries conducted from February 2014 to March 2015. This planned secondary analysis included diamniotic twin pregnancies from 26 0/7 through 31 6/7 weeks of gestation.

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Objectives: To evaluate the revision of methodology of the clinical practice guidelines (CPG) of the French National College of Gynecologists and Obstetricians (CNGOF).

Method: Three CPGs were organized in 2020 on the topics of severe preeclampsia, menorrhagia, and prophylactic surgery according to AGREE II (Apraisal of Guidelines for Research & Evaluation). Questions were presented in PICO (Population, Intervention, Comparison, Outcome) format and the grading of scientific evidence was based on the GRADE (Grading of Recommendation Assessment, Development and Evaluation) method.

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