Publications by authors named "Muzafar G A Wahab"

Sudden unexpected clinical deterioration or cardiorespiratory instability is common in neonates and is often referred as a "crashing" neonate. The established resuscitation guidelines provide an excellent framework to stabilize and evaluate these infants, but it is primarily based upon clinical assessment only. However, clinical assessment in sick neonates is limited in identifying underlying pathophysiology.

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A term infant girl was admitted for evaluation of severe thrombocytopenia. She also had purpura-like skin lesions. A complete blood count showed a platelet count of 40×10/L (normal value: 150 to 400×10/L).

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Objective: We sought to evaluate physiological cardiorespiratory implications of high pressures (>8 cmH O) on continuous positive airway pressure (CPAP) in preterm neonates.

Methods: Fifteen preterm neonates at postmenstrual age ≥32 weeks on CPAP 5 cmH O were enrolled. Pressures were increased by 2 cmH O increments until 13 cmH O.

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Background: Growth of neonatal intensive care units in number and size has raised questions towards ability to maintain continuity and quality of care. Structural organization of intensive care units is known as a key element for maintaining the quality of care of these fragile patients. The reconstruction of megaunits of intensive care to smaller care units within a single operational service might help with provision of safe and effective care.

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