Publications by Muza M Kokhan

Publications by authors named "Muza M Kokhan"

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Long-term data on the proposed adalimumab biosimilar BCD-057 in patients with moderate to severe psoriasis: A randomized controlled trial.

Alexey V Samtsov Andrey L Bakulev Vladislav R Khairutdinov Muza M Kokhan Tat'yana V Korotaeva

PLoS One

March 2022

Article Synopsis

The study aimed to compare the effectiveness, safety, and pharmacokinetics of BCD-057 with the well-known drug adalimumab (iADA) for treating moderate to severe plaque psoriasis.
A total of 346 patients participated, with 60% of BCD-057 users achieving significant improvement at week 16, showing both drugs are similarly effective over time.
Both treatments exhibited comparable safety profiles, and switching from iADA to BCD-057 did not impact the patients' immune response, confirming their similarity.

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Efficacy and Safety of Netakimab, A Novel Anti-IL-17 Monoclonal Antibody, in Patients with Moderate to Severe Plaque Psoriasis. Results of A 54-Week Randomized Double-Blind Placebo-Controlled PLANETA Clinical Trial.

Luís Puig Andrey L Bakulev Muza M Kokhan Alexey V Samtsov Vladislav R Khairutdinov

Dermatol Ther (Heidelb)

August 2021

Introduction: Netakimab (NTK), an original humanized anti-interleukin-17 monoclonal antibody, showed therapeutic efficacy in moderate-to-severe plaque psoriasis in a phase 2 clinical study. Herein we report the results of 54 weeks of a phase 3 PLANETA trial aimed to evaluate the efficacy and safety of two NTK regimens vs. placebo.

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