Getah virus (GETV) is a mosquito-borne alphavirus that can cause disease outbreaks in domesticated mammals. The E1 protein of GETV plays a crucial role in mediating the fusion of viruses and host cells. In this study, the recombinant GETV E1 protein was expressed and administered to BALB/c mice.
View Article and Find Full Text PDFGetah virus (GETV) is a re-emerging mosquito-borne RNA virus that induces fever, hind limb edema, swollen submandibular lymph nodes, and urticaria in horses. In pigs, the virus often results in stillbirths among pregnant sows, and neurological symptoms leading to death in piglets. Currently, there are no specific treatments or drugs available for GETV infection.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
July 2024
Getah virus (GETV) is an emerging mosquito-borne alphavirus that can infect horses, pigs and other animals. Given the public health threat posed by GETV, research on its pathogenesis, diagnosis and prevention is urgently needed. In the current study, prokaryotic expression systems were used to express the capsid protein of GETV.
View Article and Find Full Text PDFThis paper proposes a scheme to reduce big graphs to small graphs. It contracts obsolete parts and regular structures into supernodes. The supernodes carry a synopsis for each query class in use, to abstract key features of the contracted parts for answering queries of .
View Article and Find Full Text PDFWe present O(10^{15}) string compactifications with the exact chiral spectrum of the standard model of particle physics. This ensemble of globally consistent F-theory compactifications automatically realizes gauge coupling unification. Utilizing the power of algebraic geometry, all global consistency conditions can be reduced to a single criterion on the base of the underlying elliptically fibered Calabi-Yau fourfolds.
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