Publications by authors named "Muwafaq Al Hyari"
J Adv Pharm Technol Res
July 2024
Article Synopsis
- Diabetes management is crucial, and therapeutic drug monitoring, particularly for medications like metformin and glimepiride, can help maintain optimal dosages in patients.
- A study involving 106 type 2 diabetes patients used a validated LC-MS/MS method to measure drug levels and examined the relationship between drug concentration and genetic mutations, particularly focusing on the SULT1A1 genotype.
- Findings indicated a potential correlation between metformin levels and genetic factors, suggesting that tailored (genotype-guided) drug therapy could enhance treatment effectiveness and reduce adverse effects.
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