Digital insights into Pseudomonas aeruginosa PBH03: in-silico analysis for genomic toolbox and unraveling cues for heavy metal bioremediation.

Background: The genomes of publicly available electroactive Pseudomonas aeruginosa strains are currently limited to in-silico analyses. This study analyzed the electroactive Pseudomonas aeruginosa PBH03 genome using comparative in-silico studies for biotechnological applications.

Objective: Comparative in-silico and experimental analyses were conducted to identify the novel traits of P.

Chimeric versus Multiple Flaps for Composite Oral Cavity Defects: A Systematic Review and Meta-Analysis.

Objectives: Complex head and neck defects involving composite defects can be reconstructed using chimeric flaps or multiple flaps with separate anastomoses. Limited comparisons exist between chimeric and multiple flap reconstructions. We compare outcomes between chimeric and multiple flap reconstructions in oral cavity reconstruction.

Case Report: Life-Threatening Fluoxetine-Linked Postoperative Bleeding Informed by Pharmacogenetic Evaluation.

Background: Selective serotonin reuptake inhibitors (SSRI) are commonly used for the treatment of depression and anxiety. Inhibition of serotonin reuptake in platelets increases bleeding risk in patients taking SSRIs.

Case: Here, we present the case of a 52-year-old patient who developed severe postsurgical bleeding requiring blood transfusion following panniculectomy.

Citrate Synthase Overexpression of Increases Succinate Production from Acetate in Microaerobic Cultivation.

Acetate is an end-product of anaerobic biodegradation and one of the major metabolites of microbial fermentation and lingo-cellulosic hydrolysate. Recently, acetate has been highlighted as a feedstock to produce value-added chemicals. This study examined acetate conversion to succinate by citrate synthase ()-overexpressed under microaerobic conditions.

Modification of 3D Printable Polymer Filaments for Radiation Shielding Applications.

There is a growing need to develop lead-free shielding materials that are safe, low weight, durable, environmentally friendly, chemically and mechanically stable and customizable for specific applications. Fused deposition modeling (FDM), an additive manufacturing technique based on the extrusion of a thermoplastic filament into a 3D printed object one layer at a time, could be employed well in applications involving ionizing radiation due to its relatively low cost, design flexibility and high manufacturing precision. This study aimed at developing 3D printing composites that contain Titanium dioxide as a filler agent for shielding in a medical radiation environment.

Feasibility of outpatient hybrid brachytherapy for cervical cancer with minimal sedation: Results from a single-institutional protocol.

Purpose: Pain control techniques during high-dose-rate hybrid intracavitary-interstitial brachytherapy (HBT) for cervical cancer vary widely, with many centers opting for general anesthesia (GA) or conscious sedation (CS). Here, we describe a single-institutional series of patients treated with HBT and ASA-defined minimal sedation, utilizing oral analgesic and anxiolytic medications in substitution for GA or CS.

Material And Methods: The charts of patients who underwent HBT treatments for cervical cancer from June 2018 to May 2020 were retrospectively reviewed.

High Dose Rate Brachytherapy for Inoperable Endometrial Cancer: a Case Series and Systematic Review of the Literature.

Endometrial cancer is a common gynaecological cancer, is typically early stage and treated with surgery. For patients where surgery is difficult or dangerous, definitive radiation therapy is the next best option. This study included a single institution case series (step 1) and a systematic review of the literature (step 2).

Comparing outcomes in patients with end-stage chronic obstructive pulmonary disease: single versus bilateral lung transplants.

Objectives: Debate continues on whether a bilateral (BLT) or a single lung transplantation (SLT) is preferred for patients with end-stage chronic obstructive pulmonary disease (COPD). The purpose of this study is to examine the interplay between patient age and transplant type on survival outcomes.

Methods: We performed a retrospective study of lung transplants for COPD at our centre from February 2012 to March 2020 (n = 186).

Enabling anoxic acetate assimilation by electrode-driven respiration in the obligate aerobe, Pseudomonas putida.

This study examined the obligate aerobe, Pseudomonas putida, using acetate as the sole carbon and energy source, and respiration via an anode as the terminal electron acceptor under anoxic conditions. P. putida showed significantly different acetate assimilation in a closed-circuit microbial fuel cell (CC-MFC) compared to an open circuit MFC (OC-MFC).

Discordance in Perceptions of Barriers to Breast Cancer Treatment Between Hispanic Women and Their Providers.

Despite comparable screening and incidence rates that are 26% below that of non-Hispanic Whites, Hispanic women present with breast cancer at more advanced stages of disease, representing a continuing and troubling health disparity for this population. Reducing these disparities warrant more innovative research approaches to better understand perspectives of Hispanic patients regarding barriers to treatment and how these perspectives compare to those of their providers. A pilot qualitative study was conducted at a major urban cancer center in Arizona that measured both patient and provider perspectives regarding barriers to treatment.

Porous carbon supported calcium oxide for CO adsorption and separation of CO/CH.

Calcium oxide incorporated porous carbon materials were synthesized by the impregnation method to study CO adsorption and separation of CO/CH. The X-ray diffraction, Raman analysis, N isotherms at 77 K, and SEM with EDX analysis were used to characterize synthesized materials. XRD and N isotherm results have confirmed that synthesized carbon has porosity, and EDX analysis has reported that the presence of CaO on porous carbon.

Disintegration of Flower-Like MoS₂ to Limply Allied Layers on Spherical Nanoporous TiO₂: Enhanced Visible-Light Photocatalytic Degradation of Methylene Blue.

MoS₂/TiO₂ heterostructure with enhanced photocatalytic activity was successfully synthesized by hydrothermal method. The segmentation of flower-like MoS₂ structure resulted, during the hydrothermal condition in the presence of spherical nanoporous TiO₂ as a growing matrix. A pool of larger spherical TiO₂ particle induces a strain effect, which restricted the size of MoS₂.

Efficient Vapor-Phase Selective Hydrogenolysis of Bio-Levulinic Acid to γ-Valerolactone Using Cu Supported on Hydrotalcite Catalysts.

In this work, Cu nanoparticles (Cu NPs, 2-20 nm) supported on Hydrotalcite catalysts exhibit enhanced selectivity for γ-valerolactone (GVL) during hydrogenolysis of levulinic acid (LA). At 260 °C, over 3 wt% Cu achieved 87.5% of LA conversion with a maximum GVL selectivity (95%).

High Catalytic Activity of C Pd Encapsulated in Metal-Organic Framework UiO-67, for Tandem Hydrogenation Reaction.

Metal nanoparticles (NPs) stabilized by MOFs are very promising for catalysis, whereas introduction of C into MOFs has been very rarely used, and there was no report for their cooperative catalysis in organic syntheses. In this work, C @UiO-67 was synthesized by a one-pot method, so that C is uniformly distributed on UiO-67 in molecular form. Pd NPs coordinating with C have been successfully embedded into the framework.

Predominated Thermodynamically Controlled Reactions for Suppressing Cross Nucleations in Formation of Multinary Substituted Tetrahedrite Nanocrystals.

Group I-II-V-VI semiconducting CuM SbS (M = Zn, Cd, Mn and Cu) substituted tetrahedrite nanostructures remain a new class of multinary materials that have not been widely explored yet. Having different ions, the formation process of these nanostructures always has the possibility of formation of cross nucleations. Minimizing the reaction time, herein, a predominantly thermodynamic control approach is reported, which decouples the quaternary nucleations from their possible cross nucleations.

Custom mold applicator high-dose-rate brachytherapy for nonmelanoma skin cancer-An analysis of 273 lesions.

Purpose: Nonmelanoma skin cancer is the most commonly diagnosed malignancy in the United States. A modern version of surface brachytherapy, "topographic applicator brachytherapy" (TAB), can be used to treat early-stage nonmelanoma skin cancer (ES-NMSC). The purpose of this study was to evaluate the acute toxicity, chronic toxicity, and recurrence rates of patients with ES-NMSC treated with TAB.

Skin surface brachytherapy: A survey of contemporary practice patterns.

Purpose: The aim of this study was to define current patterns of care among radiation oncologists who use skin surface brachytherapy for the treatment of cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC) in academic and community settings.

Methods And Materials: A 30-question electronic survey was administered to clinician members of the American Brachytherapy Society. The respondents were asked to provide details regarding their clinical practice and their approach to skin surface brachytherapy.

Methods to determine response factors for infrared gas imagers used as quantitative measurement devices.

Unlabelled: Response factors (RF) can be used to characterize relative sensitivity of one compound vs. another compound for the same measurement instrument. Use of RF allows the analysts/operators to calibrate the instrument with one compound and make measurement for a large number of compounds.

A reagentless non-enzymatic hydrogen peroxide sensor presented using electrochemically reduced graphene oxide modified glassy carbon electrode.

Herein, we report a simple, facile and reproducible non-enzymatic hydrogen peroxide (H2O2) sensor using electrochemically reduced graphene oxide (ERGO) modified glassy carbon electrode (GCE). The modified electrode was characterized by Fourier transform infrared (FT-IR), UV-Visible, scanning electron microscopy (SEM) and atomic force microscopy (AFM) techniques. Cyclic voltammetric (CV) analysis revealed that ERGO/GCE exhibited virtuous charge transfer properties for a standard redox systems and showed excellent performance towards electroreduction of H2O2.

Multiple dural-based hemangiopericytomas.

Here we report the case of a 57-year-old man who underwent resection of a dural-based hemangiopericytoma (HPC) in the left frontoparietal region. The patient was treated with radiation therapy and remained symptom-free for 10 years. At 67 years of age, he presented with a mass in the left frontal region near the same area as the first tumor, in addition to a separate smaller mass in the right middle cranial fossa.

American Brachytherapy Society consensus guidelines for thoracic brachytherapy for lung cancer.

Purpose: To update brachytherapy recommendations for pretreatment evaluation, treatment, and dosimetric issues for thoracic brachytherapy for lung cancer.

Methods And Materials: Members of the American Brachytherapy Society with expertise in thoracic brachytherapy updated recommendations for thoracic brachytherapy based on literature review and clinical experience.

Results: The American Brachytherapy Society consensus guidelines recommend the use of endobronchial brachytherapy for disease palliation in patients with central obstructing lesions, particularly in patients who have previously received external beam radiotherapy.

Antioxidant and protective effects of Phytocee(™) against carbon tetrachloride-induced oxidative stress.

Background: This study evaluated the antioxidant potential of a polyherbal formulation (Phytocee(™)) in the rodent model.

Materials And Methods: Four groups of rats (n = 6) were pretreated with Vitamin C (20 mg/kg) or Phytocee(™) (20, 100, and 200 mg/kg), respectively for 10 days. Oxidative stress in rat liver was induced by administration of carbon tetrachloride (CCl4) at 2 ml/kg as a single dose orally to all groups except the vehicle control group.