Publications by authors named "Mutsumi Yokoyama"
Background: Anticoagulation therapy, especially using heparin or recently developed oral direct factor Xa inhibitors (DiXals), is recommended as first-line treatment for cancer-related venous thromboembolism (VTE). However, the preventive efficacy of these anticoagulants for cancer-associated ischemic stroke is still unknown. We retrospectively investigated the efficacy of subcutaneous unfractionated heparin (UFH) and DiXals for preventing the recurrence of cancer-associated cryptogenic ischemic stroke with VTE.
View Article and Find Full Text PDFA 48-year-old woman was admitted to our hospital because of headache and fever. She was diagnosed with aseptic meningitis. Five days later, she had a seizure and developed left hemiparesis.
View Article and Find Full Text PDFBackground: Nonvitamin K antagonist oral anticoagulants (NOACs) are considered superior, or at least noninferior, to warfarin in preventing stroke or systemic embolism in patients with nonvalvular atrial fibrillation. Here, we recruited acute ischemic stroke patients with nonvalvular atrial fibrillation and at least one cerebral microbleed (CMB), and evaluated the proportion of patients who had an increased number of CMBs (%) after receiving anticoagulant therapy with NOACs or with warfarin for 12 months.
Methods: This was a multicenter, prospective, observational cohort study at 20 centers, conducted between 2015 and 2017, in which we recruited 85 patients with at least one CMB detected by 1.
Article Synopsis
- The YAMATO study explored whether administering edaravone (a free radical scavenger) with or before tissue-type plasminogen activator (tPA) improves early recanalization in stroke patients with major artery blockages.
- Conducted at 17 hospitals in Japan, the study involved 165 patients with strokes due to M1 or M2 artery occlusions, randomly assigned to receive edaravone before/during or after tPA.
- Results showed no significant differences in early recanalization rates, hemorrhage occurrences, or favorable outcomes between the groups, indicating that the timing of edaravone infusion does not impact tPA therapy effectiveness.
The aim of this study was to analyze the pattern of magnetic resonance diffusion-weighted imaging (DWI) findings in status epilepticus in terms of clinical characteristics. Participants comprised 106 patients with status epilepticus who were admitted to our hospital and underwent DWI. Forty-five patients (42.
View Article and Find Full Text PDFBackground And Purpose: Arterial spin labeling (ASL) is a non-invasive modality of magnetic resonance imaging (MRI) used to evaluate cerebral perfusion without a contrast agent. The usefulness of ASL for diagnosis in the acute phase of late seizure after stroke was evaluated.
Methods: Twelve consecutive patients diagnosed with late seizure after stroke were enrolled in this study.