Publications by authors named "Mutsumasa Yoh"
Third nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2020 and 2021: Antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus.
J Infect Chemother
April 2024
Article Synopsis
- A nationwide surveillance in Japan studied the antimicrobial susceptibility of bacteria in acute uncomplicated cystitis, focusing on E. coli, K. pneumoniae, and S. saprophyticus, between April 2020 and September 2021.
- The study isolated 823 bacterial strains from urine samples of 848 patients, with a majority being E. coli (92.9%), and determined susceptibility to 18 antibacterial agents.
- Results showed a concerning increase in fluoroquinolone-resistant E. coli and extended-spectrum β-lactamase (ESBL)-producing E. coli, especially in postmenopausal women, highlighting the need for clinicians to adapt their antibiotic choices due to rising resistance rates.
Neisseria gonorrhoeae is one of the important pathogens of sexually transmitted infections. N. gonorrhoeae is rapidly becoming antimicrobial resistant, and there are few drugs that are effective in the initial treatment of gonorrhea.
View Article and Find Full Text PDFNationwide surveillance of the antimicrobial susceptibility of Chlamydia trachomatis from male urethritis in Japan: Comparison with the first surveillance report.
J Infect Chemother
January 2022
Article Synopsis
- The Urogenital Sub-committee and Surveillance Committee of various Japanese health organizations conducted a nationwide study to assess how susceptible Chlamydia trachomatis is to different antibiotics by collecting clinical samples from 26 hospitals between May 2016 and July 2017.
- The study measured the minimum inhibitory concentrations (MICs) for a range of antibiotics, finding no resistant strains to fluoroquinolones, tetracyclines, or macrolides, while solithromycin showed particularly favorable MIC values.
- However, the MIC for azithromycin was slightly higher than in previous reports, suggesting the need for ongoing monitoring of its susceptibility.
Second nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by Japanese Surveillance Committee from 2015 to 2016: antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus.
J Infect Chemother
June 2019
The Japanese Surveillance Committee conducted a second nationwide surveillance of antimicrobial susceptibility patterns of uropathogens responsible for acute uncomplicated cystitis (AUC) in premenopausal patients aged 16-40 years old at 31 hospitals throughout Japan from March 2015 to February 2016. In this study, the susceptibility of causative bacteria (Escherichia coli, Klebsiella pneumoniae, Staphylococcus saprophyticus) for various antimicrobial agents was investigated by isolation and culturing of organisms obtained from urine samples. In total, 324 strains were isolated from 361 patients, including E.
View Article and Find Full Text PDFBackground: Gonococcal infections are difficult to treat because of their multidrug antimicrobial resistance. The outbreak of antimicrobial-resistant Neisseria gonorrhoeae has begun in Asia and particularly in Japan. Therefore, it is very important that we understand the trend of antimicrobial resistance of N.
View Article and Find Full Text PDFArticle Synopsis
- * A surveillance study conducted in Japan collected urethral discharge samples from patients in 2009 and 2012 to test for antibiotic resistance in C. trachomatis isolates.
- * Results showed that no resistant strains were found against common antibiotics like fluoroquinolones, tetracyclines, or macrolides during both years of the study.
Worldwide, the most important concern in the treatment of sexually transmitted infections is the increase in antimicrobial resistant Neisseria gonorrhoeae strains including resistance to cephalosporins, penicillins, fluoroquinolones or macrolides. To investigate the trends of antimicrobial susceptibility among N. gonorrhoeae strains isolated from male patients with urethritis, a Japanese surveillance committee conducted the second nationwide surveillance study.
View Article and Find Full Text PDFNeisseria gonorrhoeae is one of the most important pathogens causing sexually transmitted infection, and strains that are resistant to several antimicrobials are increasing. To investigate the trends of antimicrobial susceptibility among N. gonorrhoeae strains isolated from male patients with urethritis, a Japanese surveillance committee conducted the first nationwide surveillance.
View Article and Find Full Text PDF[Analysis of factors affecting reccurence and prognosis of superficial bladder cancer--study of 800 patients--].
Nihon Hinyokika Gakkai Zasshi
January 2006
Purpose: The purpose of the present paper was to evaluate clinical factors responsible for recurrence and prognosis of superficial bladder cancer.
Subjects And Method: We reviewed date from 800 patients who were initially treated between 1991 and 2000. Recurrent and prognostic factors were examined with univariate and multivariate analysis.