Human exposure to aflatoxins in Zimbabwe.

In this communication, we report the detection of aflatoxins in human urine and breast milk. The 2553 urine samples were collected from donors of different ages and sexes at centres throughout Zimbabwe, while 54 breast milk samples were collected from breast feeding mothers. The most predominant aflatoxins found were AFM and AFG.

A survey of urinary aflatoxin in Zimbabwe.

In this study, 1228 urine samples were collected from different centres in Zimbabwe and were analysed for aflatoxin contamination. The urine samples were extracted with chloroform and analysed by thin layer chromatography and high-performance liquid chromatography. The most commonly observed contaminant was aflatoxin M1, at an average concentration of 4.

Aflatoxin detected in human breast milk by immunoassay.

Several epidemiological studies have shown a positive association between dietary exposure to aflatoxin (AF) and an increased incidence of primary hepatocellular carcinoma (PHC). One area in which little information is available is the exposure of newborn children to AF in human breast milk. We report the development, validation and application of an enzyme-linked immunosorbent assay (ELISA) to the detection of AF in human breast milk.