Publications by authors named "Muthuperumal Prakash"

Background: In India, approximately 3.5 million children are affected by Developmental Delay (DD), often stemming from preterm births. These delays contribute to neurological and motor development delays, placing a significant financial burden on families.

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Background: Approximately 1 in 8 children under the age of 6 in Tamil Nadu are diagnosed with neurodevelopmental disorders (NDD), yet only a fraction of these children receives proper medical care. The unequal distribution of healthcare services is mainly due to the lack of accessibility, especially in rural areas, leading to a significant burden on caregivers. This research aims to alleviate caregiver burden and reduce disability in preschool children by establishing model clinics or specialized outreach centers in rural villages, supported by SRM Institute of Science and Technology under the Unnat Bharat Abhiyan Scheme.

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Article Synopsis
  • - Rituximab (RTX) shows potential as a treatment for idiopathic membranous nephropathy (IMN), but its high cost and severe side effects have led to exploring low-dose RTX as a viable option.
  • - A systematic review analyzed 16 studies that evaluated the effects of low-dose RTX on adult IMN patients, with main outcomes focused on complete and partial response rates and secondary effects on kidney function and protein levels.
  • - Results indicated that low-dose RTX treatments resulted in significant rates of complete remission, improved serum albumin levels, and reduced protein-creatinine ratio, though a concerning trend of lower estimated glomerular filtration rate (eGFR) was observed post-treatment in second-line therapy patients
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Introduction: The Siddha system of medicine (SSM) is one of the Indian Systems of Medicine (ISM). In recent times, it has received adequate support from the Indian Ministry of Ayush. Like many such indigenous systems of medicine globally, the SSM is based on its own theoretical principles, philosophy, and methods of practice.

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Data on the prevalence of cardiac failure with preserved ejection in the haemodialysis population, which impacts treatment strategy, mortality, and morbidity, are scarce. Estimate the prevalence of heart failure with preserved ejection fraction (HFpEF) in haemodialysis patients Classify cardiac failure and ascertain the risk factors influencing HFpEF in haemodialysis patients. All consenting individuals on haemodialysis over 18 years of age were included.

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Background: Siddha Medicine system is one among the oldest traditional systems of medicines in India and has its entire literature in the Tamil language in the form of poems ( in tamil). Even if the siddha poems are available in public domain, they are not known to other parts of the world because, researchers of other languages are not able to understand the contents of these poems and there exists a language barrier. Hence there is a need to develop a system to extract structured information from these texts to facilitate searching, comparing, analysis and implementing.

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Background: Mass gathering events carry a risk of public health emergencies such as outbreaks of infectious diseases, stampedes, and injuries and pose an increased risk for individuals with non-communicable diseases. India celebrates many festivals mass gatherings. However, operational research on syndromic surveillance during such events is limited.

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