Publications by authors named "Muthukumar Balakrishnan"

Article Synopsis
  • Community-Acquired Acute Kidney Injury (CA-AKI) is linked to high hospital mortality and this study aimed to analyze its clinical profiles and outcome factors among patients.
  • Conducted from 2021 to 2022, the study involved 283 participants and utilized KDIGO criteria to categorize patients, collecting data on demographics, clinical features, and outcomes over three months.
  • Findings revealed that CA-AKI is prevalent among younger males, with sepsis as the leading cause; 30.4% of patients died within three months, underscoring the need for improved prevention and early detection strategies.
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Article Synopsis
  • A case study of a 32-year-old male with a second kidney transplant revealed that herpes simplex virus-2 (HSV-2) caused both esophageal ulcers and acute graft dysfunction.
  • Early diagnosis and treatment with intravenous acyclovir were crucial for recovering the kidney graft, emphasizing the need to consider rare viral infections in post-transplant care.
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Crude oil hydrocarbons are considered major environmental pollutants and pose a significant threat to the environment and humans due to having severe carcinogenic and mutagenic effects. Bioremediation is one of the practical and promising technology that can be applied to treat the hydrocarbon-polluted environment. In this present study, rhamnolipid biosurfactant (BS) produced by Pseudomonas aeruginosa PP4 and green synthesized iron nanoparticles (G-FeNPs) from Lawsonia inermis was used to evaluate the biodegradation efficiency (BE) of crude oil.

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Poly aromatic hydrocarbons (PAHs) are considered as hazardous compounds which causes serious threat to the environment dua to their more carcinogenic and mutagenic impacts. In this study, Pseudomonas aeruginosa PP4 strain and synthesized iron nanoparticles were used to evaluate the biodegradation efficiency (BE %) of residual anthracene. The BE (%) of mixed degradation system (Anthracene + PP4+ FeNPs) was obtained about 67 %.

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Introduction: Ointments are generally used as a therapeutic agent for topical medication or transdermal drug delivery, such as wound healing and skin lesions.

Methods: In this study, plant extract (0.7 g/mL) was used to prepare herbal-infused oil as the oil phase and gelatin-stabilized silver nanoparticle (G-AgNPs) (0.

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Article Synopsis
  • The study focused on the surveillance of Arteriovenous Fistula (AVF) to detect early dysfunction and prolong access-patency, comparing clinical examination (CE), doppler, and fistulogram as detection methods.
  • Conducted between December 2019 and April 2021, it involved patients with matured AVF and assessed secondary failure rates using these three methods, with the fistulogram considered the gold standard.
  • Results showed that out of 88 analyzed patients at six months, 86.4% had patent AVFs, 9.1% experienced secondary failure, and the combination of CE and doppler had the highest sensitivity for detecting issues in AVF.
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This study aimed to carry out the bioaugmentation of crude oil/motor oil contaminated soil. The mixture of novel strains Pseudomonas aeruginosa PP3 and Pseudomonas aeruginosa PP4 were used in this bioaugmentation studies. The four different bioaugmentation systems (BS 1-4) were carried out in this experiment labelled as BS 1 (Crude oil contaminated soil), BS 2 (BS 1 + bacterial consortia), BS 3 (Motor oil sludge contaminated soil), and BS 4 (BS 3 + bacterial consortia).

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Introduction: Since COVID-19 has been announced as a pandemic, outcome of dialysis patients in terms of morbidity and mortality from India is lacking. We studied the clinical, epidemiological features of COVID-19 along with outcome in terms of mortality in our dialysis cohort.

Methods: Data of End-Stage Kidney Disease (ESKD) patients who were admitted in COVID-19 designated hospital block as positive and suspected patients from 1 April 2020 to 31 July 2020 was retrieved.

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Crude oil contaminant is one of the major problem to environment and its removal process considered as most challenging tool currently across the world. In this degradation study, crude oil hydrocarbons are degraded on various pH optimization conditions (pH 2, 4,6,7,8 and 10) by using two biosurfactant producing bacterial strains Pseudomonas aeruginosa PP3 and Pseudomonas aeruginosa PP4. During crude oil biodegradation, degradative enzymes alkane hydroxylase and alcohol dehydrogenase were examined and found to be higher in PP4 than PP3.

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In this study, two biosurfactant producing Pseudomonas aeruginosa sp. were isolated from motor oil contaminated soil for crude oil, alkane and PAH degradation studies. Metagenomics analysis identified as proteobacteria phyla was the dominant.

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The biological denitrification in the presence of gCN doped TiO composite was investigated through series of batch experiment. gCN doped TiO was synthesized and characterized by FT-IR, XRD, SEM-EDAX and the prepared composite used as electron donor for the enhancement biological denitrification. The role of extracellular polymeric substances in the biological nitrate reduction and electron transfer process has been elucidated.

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Hydrocarbons and their derivative compounds are recalcitrant in nature and causing adverse impacts to the environment and are classified as important pollutants. Removal of these pollutants from the atmosphere is a challenging process. Hydrophobic organic pollutants (HOPs) including crude oil, diesel, dotriacontane (C), and tetracontane (C) are subjected to the biodegradation study by using a bacterial consortium consist of Bacillus subtilis, Pseudomonas stutzeri, and Acinetobacter baumannii.

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