[Contribution of array CGH in the management of fetal nuchal translucency].

Objectives: Increased nuchal translucency and cystic hygroma have a neonatal prognosis, when the karyotype is normal, which depends on the findings during the medical follow-up. Array comparative genomic hybridization (aCGH) has been systematically included in this follow-up by prenatal diagnosis teams. There are no guidelines and little information on the advantages of carrying out this test systematically.

An Automatic Method for the Segmentation and Classification of Imminent Labor Contraction From Electrohysterograms.

Objective: Preterm birth is the first cause of perinatal morbidity and mortality. Despite continuous clinical routine improvements, the preterm rate remains steady. Moreover, the specificity of the early diagnosis stays poor as many hospitalized women for preterm delivery threat finally deliver at term.

Impact of establishment of a color code in emergency caesareans in secondary health care maternity.

In 2008, a tertiary health care maternity set up a colour code organization for emergency caesarean to reduce the delay between decision and birth to thirty minutes. The aim of this study is to determine the feasibility of the implementation in secondary health care maternity. MATERIALS AND METHODS: This retrospective study was conducted in secondary health care maternity and it was divided in two phases: phase I corresponding to the period before the implementation of colour code and phase II, to the period after the implementation of colour code.

Automated electrohysterographic detection of uterine contractions for monitoring of pregnancy: feasibility and prospects.

Background: Preterm birth is a major public health problem in developed countries. In this context, we have conducted research into outpatient monitoring of uterine electrical activity in women at risk of preterm delivery. The objective of this preliminary study was to perform automated detection of uterine contractions (without human intervention or tocographic signal, TOCO) by processing the EHG recorded on the abdomen of pregnant women.

One-Year Outcome for Congenital Diaphragmatic Hernia: Results From the French National Register.

Objective: To evaluate the status of congenital diaphragmatic hernia (CDH) management in France and to assess predictors of adverse outcomes.

Study Design: We reviewed the first-year outcome of all cases of CDH reported to the French National Register in 2011.

Results: A total of 158 cases were included.

The impact of using electrical impedance spectroscopy (ZedScan) on the performance of colposcopy in diagnosing high grade squamous lesions of the cervix.

Objectives: To determine the efficacy of colposcopy plus ZedScan, which measures changes in tissue electrical impedance, for detecting intraepithelial high-grade lesions compared to colposcopy alone.

Methods: A prospective study conducted at a university hospital colposcopy clinic. Patients referred following abnormal cervical cytology or colposcopic follow up were examined by colposcopy plus ZedScan to assess the cervix.

Impact of anaesthesia mode on evaluation of LEEP specimen dimensions.

Objectives: To study the influence of anaesthesia (local by cervical block vs. general or spinal anaesthesia) on height and volume of resection specimens in case of conization treatment for cervical intraepithelial neoplasia (CIN).

Methods: Prospective observational study of all patients who underwent a first treatment by loop electrosurgical excision procedure (LEEP) for CIN.

Maintenance nifedipine therapy for preterm symptomatic placenta previa: A randomized, multicenter, double-blind, placebo-controlled trial.

Objective: To assess the impact of maintenance nifedipine therapy on pregnancy duration in women with preterm placenta previa bleeding.

Methods: PPADAL was a randomized, double-blind, placebo-controlled trial conducted between 05/2008 and 05/2012 in five French hospitals. The trial included 109 women, aged ≥ 18 years, with at least one episode of placenta previa bleeding, intact membranes and no other pregnancy complication, at gestational age 24 to 34 weeks and after 48 hours of complete acute tocolysis.

Better pregnancy monitoring using nonlinear correlation analysis of external uterine electromyography.

The objective of this paper is to evaluate the novel method for analyzing the nonlinear correlation of the uterine electromyography (EMG). The application of this method may improve monitoring in pregnancy, labor detection, and preterm labor detection. Uterine EMG signals recorded from a 4 × 4 matrix of electrodes on the subjects' abdomen are used here.

[Evolution of electrohysterogram signals synchronization according to term of pregnancy: interest for preterm labor diagnosis].

Objectives: Our study focuses on the analysis of the uterine electromyogram recorded on women during pregnancy. We were interested in evaluating the synchronization of this electrical signal at various terms in order to follow evolution of synchronization as labor approaches. This study attempts to deepen our understanding of the myometrial maturation close to labor and to provide reliable parameters for improving preterm labor diagnosis.

[Should CIN 2 and 3 be treated the same way?].

Although spontaneous regression of cervical intraepithelial neoplasia type 2 (CIN 2) occurs in 40% of cases over a 2 years period, such diagnosis commonly requires the use of excisional techniques exposing to genuine obstetrical and neonatal morbidity as well as the risk of unsatisfactory post-treatment colposcopy. Recent advances in knowledge about CIN 2 natural history and morbidity of conservative therapies brings out the need to optimize therapeutics indications and to reconsider the use of ablative techniques. In order to allow for the lack of histological analysis and final diagnosis, it is therefore crucial not to misdiagnose microinvasive cervical disease.

Clinical significance of terminal syringomyelia in association with pediatric tethered cord syndrome.

An association between terminal syringomyelia (TS) and tethered cord syndrome (TCS) has been recognized. The clinical significance of TS and the need for concurrent treatment is not known. Thirty-four patients with TCS undergoing surgery for tethered cord release were evaluated for the incidence of TS.

Management of shunt infections: a multicenter pilot study.

Object: Approximately 10% of cerebrospinal fluid (CSF) shunt operations are associated with infection and require removal or externalization of the shunt, in-hospital treatment with antibiotic agents, and insertion of a new shunt. In a previous survey, the authors identified substantial variation in the duration of antibiotic therapy as well as the duration of hospital stay. The present multicenter pilot study was undertaken to evaluate current strategies in the treatment of shunt infection.

Automating 3D meshing method for patient-specific modeling.

The purpose of this study was to develop an automating meshing method for patient-specific modeling. Three-dimensional geometries of two six-month-old infant heads were reconstructed from the CT data. Finite element meshes including cranial bone of skull, brain, and suture were generated.

Risk of pediatric head injury after motor vehicle accidents.

Object: Injury to the brain as a result of motor vehicle accidents (MVAs) represents a frequent cause of pediatric disability. The authors analyze the correlation between the relative risk of pediatric brain injury and the use of child safety seats (CSSs).

Methods: A national database of MVAs was examined to provide data for the analysis of four age categories (infant, toddler, young child, and adolescent) and four restraint categories (unrestrained, properly restrained, improperly restrained, and other).

The circle of sagittal synostosis surgery.

Sagittal synostosis, the premature closure of the sagittal suture, accounts for more than 50% of all nonsyndromic single-suture synostoses. Although no detrimental neurologic effects can be directly attributed to the synostosis, a number of patients will have relatively increased intracranial pressure. Surgical correction for sagittal synostosis has evolved from simple removal of bone strips to extensive cranial remodeling, all in a attempt to achieve a normal head shape.

Saccular aneurysm associated with posterior cerebral artery fenestration manifesting as a subarachnoid hemorrhage in a child.

Fenestrations of the cerebral arteries are uncommon, and aneurysms in association with fenestrations are even more uncommon. We report the case of a saccular aneurysm associated with a posterior cerebral artery fenestration in a child with subarachnoid hemorrhage. The patient was successfully treated with Guglielmi detachable coils.

Infantile cerebral aneurysms with visual pathway compression.

Intracranial aneurysms are rare in infancy. The commonest presentation is intracranial hemorrhage, but signs of mass effect are more frequent than in adults. We report 2 infants with cerebral aneurysms, one presenting with macrocephaly and another with strabismus.