Identifying HIV-1 Transmission Clusters in Uzbekistan through Analysis of Molecular Surveillance Data.

The CRF02_AG and sub-subtype A6 are currently the predominant HIV-1 variants in the Republic of Uzbekistan, but little is known about their time-spatial clustering patterns in high-risk populations. We have applied molecular evolution methods and network analyses to better understand the transmission patterns of these subtypes by analyzing 316 sequences obtained during the surveillance study of HIV drug resistance. Network analysis showed that about one third of the HIV infected persons were organized into clusters, including large clusters with more than 35 members.

Preparation of Aluminum-Molybdenum Alloy Thin Film Oxide and Study of Molecular CO + NO Conversion on Its Surface.

Adsorption and interaction of carbon monoxide (CO) and nitric oxide (NO) molecules on the surface of bare Al-Mo(110) system and on that obtained by its in situ oxidation have been studied in ultra-high vacuum (base pressure: ca. 10 Pa) by means of Auger and X-ray photoelectron spectroscopy (AES, XPS), low energy electron diffraction (LEED), reflection-absorption infrared and thermal desorption spectroscopy (RAIRS, TDS), and by the work function measurements. In order to achieve the Al-Mo(110) alloy the thin aluminum film of a few monolayers thick was in situ deposited onto the Mo(110) crystal and then annealed at 800 K.

Prevalence of Antiretroviral Drug Resistance Mutations Among Pretreatment and Antiretroviral Therapy-Failure HIV Patients in Uzbekistan.

To evaluate the national prevalence of antiretroviral therapy (ART)-resistant HIV-1 viruses among both ART-initiators (pretreatment drug resistance, PDR) and ART-failure HIV patients in Uzbekistan. A nation-wide, cross-sectional active HIV-1 PDR surveillance was conducted in Uzbekistan from 2015 to 2016. In total, 713 blood plasma samples from adults were collected, including samples from ART-naive patients initiating ART and ART-failure HIV patients.

[Modern problems of modelling and treatment of soft tissues abscesses].

Increase of the frequency of soft tissues pyoinflammatory diseases and purulent-septic complications against the background the antibiotic-resistance of organism dictates the necessity of search of rational new surgical technologies and preparations with the intense bactericidal effect. Period of the connective tissue (cicatrix) formation on a place of wound defect of the operated purulent abscess of soft tissue (PAST) is defined by the speed of the granulations and epithelial tissue formation. Therefore, one of the task of experimental surgery is search of new methods of the effective postoperative influence on terms of the regeneration and complete obliteration of the PAST cavity.