Publications by authors named "Mustafa Sirri Kotanoglu"
Article Synopsis
- * Out of 53 EEC samples, CD44 and CD47 were expressed in 81% of cases, while TNF-α and IL-1 showed lower positivity rates (40.5% and 42.9%, respectively), with CD44 linked to better survival rates and disease stage.
- * The results indicate that CD44 is a significant prognostic marker for survival in EEC, whereas TNF-α and IL-1 may affect prognosis in less direct ways, especially
Article Synopsis
- This study investigates the effects of pitavastatin on nerve injury in rats, focusing on electrophysiological, scintigraphic, and histopathological outcomes.
- A total of 30 Wistar albino rats were divided into three groups to evaluate the impact of pitavastatin on nerve injury over 21 days, using various analysis methods for assessment.
- Results indicated significant differences in gait parameters and histopathological measures among the groups, suggesting that pitavastatin may aid in nerve regeneration and recovery of motor function in cases of sciatic nerve injury.*
Purpose: To evaluate protective effects of dexmedetomidine, calcitriol and their combination.
Methods: Forty Wistar-albino rats were divided into 4 groups; group of Sham (Group Sham); group of dexmedetomidine (Group DEX); group of calcitriol (Group CAL) and group of dexmedetomidineandcalcitriol (Group DEX-CAL). Photographic analysis was used for macroscopic analysis and perfusion analyses were evaluated by scintigraphy.
Background/aim: Dexmedetomidine (DEX) is an alpha-2 adrenergic agonist that is commonly used as a sedative and anesthetic. The protective effects of DEX against oxidative damage under both in vitro and in vivo conditions have been demonstrated. It was aimed to evaluate and compare the protective effects of DEX and vitamin C (Vit C) on DNA against H2O2-induced DNA damage in human lymphocyte cell cultures in vitro by alkaline Comet assay.
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- - The study compared the effects of intravenous fentanyl alone (Group F) and intravenous fentanyl with bupivacaine infiltration (Group FB) on patients' hemodynamic responses during skull pin insertion in elective craniotomy procedures, involving 120 ASA I-II patients.
- - Both groups showed a significant decrease in heart rate (HR) compared to baseline after skull pin insertion, but there was no notable difference in HR between the two groups.
- - Mean arterial pressure (MAP) in Group FB was significantly lower at both 1 and 5 minutes post-insertion compared to Group F, indicating that while both methods effectively suppressed hemodynamic responses, the bupivacaine did not provide extra benefits over fent
Background And Objectives: Although epinephrine commonly is added to local anesthetics for regional anesthesia, rarely it may cause undesirable hemodynamic side effects. This study compared the hemodynamic and blockade effects of 25 and 200 microg epinephrine during axillary brachial plexus blockade with lidocaine 1.5%.
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