Publications by authors named "Mustafa Nasrat Abdulrahim"
Article Synopsis
- PCSK9, a key player in cholesterol metabolism and cardiovascular diseases, is now being studied for its role in cancer biology, influencing various cellular processes linked to tumor growth and aggressiveness.
- Research shows that PCSK9 modulates important signaling pathways (like PI3K/Akt, MAPK, and Wnt/β-catenin) that affect cell proliferation, survival, and the formation of blood vessels, alongside its effects on cholesterol homeostasis and immune system interactions.
- The potential of PCSK9 inhibitors in cancer immunotherapy is being explored, with evidence of their synergy with existing treatments, indicating that understanding PCSK9's role could lead to novel therapeutic strategies in cancer treatment.
