Publications by authors named "Mustafa Namik Oztanir"

Background: Central nervous system lymphoma (CNSL) is a devastating disease with a poor prognosis. Early diagnosis, monitoring of the treatment response, and outcome prediction carry the utmost importance in the management of patients with CNSL. Surgical biopsy is the gold standard for tissue diagnosis, however, this procedure has potential complications.

View Article and Find Full Text PDF

Aim: To investigate the presence of Sur1-Trpm4 receptors in high-grade glial tumors, and their relationship with edema volumes in preoperative magnetic resonance imaging (MRI) sequences.

Material And Methods: MRI sections were extracted from T1-weighted (T1W) and T2-weighted (T2W) sequences and fluidattenuated inversion recovery (FLAIR) images. After that, T1W 3D magnetization-prepared rapid gradient echo (MP-RAGE) sequences were taken with and without contrast medium.

View Article and Find Full Text PDF

Background: The role of Gamma Knife radiosurgery (GKRS) in recurrent glioblastoma remains unclear. The purpose of this study is to evaluate the effects of GKRS in a group of patients with recurrent glioblastoma, focusing on survival and safety.

Methods: Patients undergoing GKRS for recurrent glioblastoma between September 2014 and April 2019 were included in this study.

View Article and Find Full Text PDF

The vasospasm, which develops after subarachnoid hemorrhage (SAH), is an unenlightened table in terms of etiology and results. It is usually associated with decreased perfusion, which is associated with decreased blood flow distal to the affected artery and can be demonstrated radiologically. Acetyl-L-carnitine (ALCAR) can be found in brain tissue and easily crosses the blood-brain barrier.

View Article and Find Full Text PDF

Background And Study Aims:  Spinal cord injury (SCI) is one of the most complicated pathologies that affect active young males. miR-21 primarily regulates several cellular processes. We aimed to elucidate the regulatory role of miR-21 and test methylprednisolone as a disease-modifying agent on experimental SCI tissues.

View Article and Find Full Text PDF

Aim: To investigate the histological and biochemical neuroprotective effects of secukinumab (SEC) on cerebral ischemia-reperfusion (IR) injury in Sprague-Dawley male rats.

Material And Methods: A total of 28 Sprague-Dawley male rats were randomly and equally divided into the following four groups: Sham, SEC, IR, and IR+SEC groups. Bilateral common carotid arteries were simultaneously separated and blocked for 15 minutes using two vascular mini clips in the IR and IR+SEC groups.

View Article and Find Full Text PDF

Background: Glioma is the primary cancer of the central nervous system in adults. Among gliomas, glioblastoma is the most deadly and aggressive form, with an average life span of 1 to 2 years. Despite implementing the rigorous standard care involving maximal surgical removal followed by concomitant radiation and chemotherapy, the patient prognosis remains poor.

View Article and Find Full Text PDF
Article Synopsis
  • The study compared red and white thrombi characteristics in 81 patients who underwent carotid endarterectomy for ischemic stroke.
  • Results indicated that red thrombi (80.2%) had more unstable features than white thrombi, including higher rates of lipid core presence, plaque rupture, and inflammation, all statistically significant differences.
  • The conclusion highlighted that red thrombi pose a greater risk for ischemic cerebrovascular events, but the results are limited due to the small sample size, necessitating further research with more patients.
View Article and Find Full Text PDF

Introduction: As a supplement, beta-glucan has various therapeutic healing effects generated by the immune cells. It has been scientifically approved and proven to be a biological defense modifier. The aim of this study was to investigate the effects of beta-glucan on treatments administered in an acute otitis media model OBJECTIVES: This study investigated the effect of beta-glucan on the treatment of acute otitis media in an acute otitis media -induced animal model.

View Article and Find Full Text PDF

Introduction: RS100642, a mexiletine analogue, is a novel sodium channel blocker with neuroprotective and antioxidant activities. The protectivity of RS100642, which has been shown against focal cerebral ischemia, was investigated in global cerebral ischemia in this study.

Material And Methods: Global cerebral ischemia was induced for five minutes in adult male Wistar Albino rats via the 4-vessel occlusion method.

View Article and Find Full Text PDF

Background/aim: The present study investigated the neuroprotective effects of chrysin (CRS) following global cerebral ischemia and reperfusion (I/R) in a C57BL/J6 mouse model.

Materials And Methods: A total of 40 mice were equally divided into four groups: (1) sham-operated (SH = control), (2) global cerebral I/R (I/R), (3) CRS, and (4) CRS + I/R. In the I/R group, the bilateral carotid arteries were clipped for 15 min and the mice were treated with vehicle (corn oil) for 10 days.

View Article and Find Full Text PDF

Spinal cord haemangioblastomas are rare central nervous systems tumours, and haemorrhage.It is an uncommon occurance. We report a 28-year-old pregnant patient who presented with paraplegia due to acute haemorrhage of a spinal haemangioblastoma.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates the vertebrobasilar artery system in patients with Behçet's disease and Neuro-Behçet's disease using magnetic resonance angiography (MRA).
  • It compares 20 patients from each disease group and 19 control subjects, focusing on the diameters of various arteries in these participants.
  • Results show that the left vertebral artery is generally larger, while Neuro-Behçet's patients exhibit larger diameters in the basilar artery and some segments of the posterior cerebral artery, suggesting Behçet's can impact vascular structures.
View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionbk4p48hc8d4a7ts0gimr0up91i4h44mj): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once