Publications by authors named "Mustafa M Basree"
Boosting the Odds: Navigating Fraction Options in the Ductal Carcinoma In Situ Odyssey.
Int J Radiat Oncol Biol Phys
October 2024
Article Synopsis
- - Mammary Paget's disease (MPD) can occur as a rare sign of breast cancer recurrence, even years after initial treatment.
- - Non-cancerous conditions can mimic MPD symptoms, potentially delaying important cancer evaluations.
- - This case underscores the necessity for ongoing cancer monitoring in patients previously treated for breast cancer, highlighting that they are still at risk even if they seem cured.
Article Synopsis
- - The study aimed to determine how effective radiomics and machine learning (ML) could be in distinguishing radiation necrosis (RN) from tumor recurrence in patients who had brain metastases treated with stereotactic radiosurgery (SRS).
- - Researchers analyzed MRI images, extracting 105 radiomic features and found that 27 features from the T1-weighted images were significant in differentiating RN from recurrence, leading to a multivariable analysis with a promising accuracy rate of 76.2%.
- - The results suggest that using radiomics and ML could improve diagnostic capabilities in this context, but further research is required to confirm these findings across larger and more diverse patient groups.
Oligometastatic state is believed to potentially represent a transitional stage between early, locoregional state disease and widely metastatic disease. Historically, locoregional approaches, particularly in advanced colorectal cancers, have demonstrated efficacy in select patients with limited burden of metastatic disease. Recent strides in systemic therapies, including biomarker-based treatments and immunotherapy, alongside innovations in surgical techniques and novel locoregional approaches such as stereotactic radiotherapy and ablation, have ushered in a new era of therapeutic possibilities across all oligometastatic GI cancers.
View Article and Find Full Text PDFRecent clinical research describes a subset of glioblastoma patients that exhibit REP prior to the start of radiation therapy. Current literature has thus far described this population using clinicopathologic features. To our knowledge, this study is the first to investigate the potential of conventional radiomics, sophisticated multi-resolution fractal texture features, and different molecular features (MGMT, IDH mutations) as a diagnostic and prognostic tool for prediction of REP from non-REP cases using computational and statistical modeling methods.
View Article and Find Full Text PDFArticle Synopsis
- Paraneoplastic syndromes (PNS) are uncommon and can be difficult to identify and manage due to their complex symptoms and the need for early diagnosis.* -
- A case study is presented involving a patient with metastatic renal cell carcinoma who experienced neurological issues, specifically progressive global ataxia and sensory changes, that persist even after kidney removal.* -
- Although the patient's symptoms did not fully resolve, starting cancer-directed therapies helped stabilize his neurological decline.*
Background: A large collaborative analysis of data from 47 epidemiological studies concluded that longer duration of breastfeeding reduces the risk of developing breast cancer. Despite the strong epidemiological evidence, the molecular mechanisms linking prolonged breastfeeding to decreased risk of breast cancer remain poorly understood.
Methods: We modeled two types of breastfeeding behaviors in wild type FVB/N mice: (1) normal or gradual involution of breast tissue following prolonged breastfeeding and (2) forced or abrupt involution following short-term breastfeeding.