A new safety parameter for diagnostic ultrasound thermal bioeffects: safe use time.

It is widely accepted that diagnostic ultrasound has the potential to elevate the temperature of tissue being scanned. Because both the maximum value of the temperature rise and the temporal profile of that rise are necessary to estimate the risk correctly, the temperature rise [DeltaT(t)] at an observation point for an exposure condition is presumed to have two components, that is, DeltaT(t)=DeltaT(max)X(t). The amplitude component DeltaT(max) is the maximum value of DeltaT(t), and the exposure time component X(t) represents the time dependency of that DeltaT(t).

Evaluation of free radical formation associated with diagnostic ultrasound.

Our objective was to evaluate kidney antioxidant status in rats subjected to an ultrasound examination. Thirty rats were divided into five groups for injection of saline (S) or anesthetic (A), and application of ultrasound using different modes, B mode, pulsed wave Doppler, and continuous wave Doppler, under anesthesia. Ultrasound was performed on days 1, 3, and 5 relative to the initiation of the experiment.