Publications by authors named "Mustafa Jawad Kadham"
Exosomes are now significant players in both healthy and unhealthy cell-to-cell communication. Exosomes can mediate immune activation or immunosuppression, which can influence the growth of tumors. Exosomes affect the immune responses to malignancies in various ways by interacting with tumor cells and the environment around them.
View Article and Find Full Text PDFObjectives: Lung adenocarcinoma (LUAD) is recognized as one of the most prevalent and deadliest malignancies around the globe. The molecular mechanisms behind LUAD have not been fully elucidated. This study was launched to explore LUAD-associated hub genes and their enriched pathways using bioinformatics methods.
View Article and Find Full Text PDFAfter cardiovascular diseases, cancer is the second deadliest malignancy in the world. The current study was launched to investigate the diagnostic and prognostic landscape of Beta-actin (ACTB) via a multi-layered bioinformatics approach. ACTB expression was analyzed and validated via UALCAN, TIMER, GENT2, GEPIA, and HPA.
View Article and Find Full Text PDFArticle Synopsis
- This study explored the causal relationships between genetically predicted risk factors and nutrients with inflammatory bowel diseases (IBDs) like ulcerative colitis (UC), Crohn's disease (CD), and non-infective colitis (NIC) using Mendelian randomization analysis.
- Genetic factors such as smoking and appendectomy, along with lifestyle factors including dietary habits, breastfeeding, and physical activity, were found to influence the risk of developing UC and CD.
- The findings emphasize the importance of various nutrients and lifestyle behaviors, highlighting their significant roles as predictors for IBDs, thus providing new insights into potential preventive strategies.