Side-to-side asymmetry in lower limb strength and hamstring-quadriceps strength ratio among collegiate American football players.

[Purpose] The present study aimed to investigate the lower limbs injury risk factors that are based on conventional Hamstring to Quadriceps ratio and limb asymmetry index in varsity American football players. [Participants and Methods] Twenty-six varsity American football players aged 19-27 years and with 2.31 ± 1.

Synthesis, in vivo anticonvulsant testing, and molecular modeling studies of new nafimidone derivatives.

An estimated 50 million people suffer epilepsy worldwide and 30% of the cases do not respond to current antiepileptic drugs (AEDs). Here, we report synthesis and anticonvulsant screening of new derivatives of nafimidone, a well-known member of (arylakyl)azole anticonvulsants. The compounds showed promising protection against maximal electroshock (MES)-induced seizures in mice and rats when administered via intraperitoneal (ip) and oral route.