Protective effects of polydatin and grape seed extract in rats exposed to cadmium.

The current study aimed to investigate the protective role of polydatin (PD) and grape seed extracts (GSEs) against the effects of cadmium chlorine (CD) application in the rats. Forty-nine adult Wistar albino male rats were used in the study. Rats were assigned into control (saline), CD (5 mg/kg CdCI), PD (120 mg/kg PD), GSE (120 mg/kg GSE), CD + PD (5 mg/kg CdCI + 120 mg/kg PD), CD + GSE (5 mg/kg CdCI + 120 mg GSE), and CD + PD + GSE (5 mg/kg CdCI+120 mg/kg PD +120 mg/kg GSE) treatments ( = 7 per group).