Publications by authors named "Mustafa Ertokatlı"
[Investigation of O25b-ST131 Clone Frequency and Presence of Carbapenem and Fosfomycin Resistance Genes in Escherichia coli Isolates: First Detection of fosA3 from Escherichia coli O25bSTf131 Clone from Türkiye].
Yeliz Tanrıverdi Çaycı Kübra Hacıeminoğlu Ülker Gülşah Karacan Temür Doğa Beliz Güney Mustafa Ertokatlı
Mikrobiyol Bul
July 2023
Article Synopsis
- The Escherichia coli ST131 clone, identified as a 'high-risk pandemic clone' since 2008, significantly contributes to the global spread of antimicrobial resistance and carries genes for both virulence and antibiotic resistance.
- A study investigated the prevalence of the O25b-ST131 clone and the presence of antibiotic resistance genes in fluoroquinolone-resistant E.coli isolates from urine samples, using specific PCR methods for detection.
- Results showed that 51.2% of isolates were identified as E.coli O25b-ST131, with carbapenem and fosfomycin resistance rates at 3.41%, and specific resistance genes detected in some isolates, highlighting the concerning rise in antibiotic resistance.
Objective: Urinary tract infections are one of the most common causes of morbidity around the world. Fosfomycin is a specific broad-spectrum antibiotic used to treat these infections. However, in recent years, many studies have reported increased fosfomycin resistance in Enterobacterales isolates.
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