Int J Biol Macromol
September 2024
Histone H2B monoubiquitination in budding yeast is a highly conserved post-translational modification. It is involved in normal functions of the cells like DNA Repair, RNA Pol II activation, trans-histone H3K and H79K methylation, meiosis, vesicle budding, etc. Deregulation of H2BK123ub can lead to the activation of proto-oncogenes and is also linked to neurodegenerative and heart diseases.
View Article and Find Full Text PDFOxidative aging of bitumen is an inevitable and irreversible phenomenon. Exposure to detrimental factors such as sunlight, oxygen, and UV radiations accelerates the aging of bitumen and bituminous pavement. The aging process induces hardening and embrittlement in bitumen, leading to premature pavement failure.
View Article and Find Full Text PDFThe intricate architecture of the intestinal epithelium, crucial for nutrient absorption, is constantly threatened by environmental factors. The epithelium undergoes rapid turnover, which is essential for maintaining homeostasis, under the control of intestinal stem cells (ISCs). The central regulator, Wnt/β-catenin signaling plays a key role in intestinal integrity and turnover.
View Article and Find Full Text PDFIn this study, sugarcane bagasse (SB) was strategically subjected to a delignification process followed by the in situ growth of multi-layered molybdenum disulfide (MoS) nanosheets with hexagonal phase (2H-phase) crystal structure via hydrothermal treatment. The MoS nanosheets underwent self-assembly to form nanoflower-like structures in the aligned cellulose inter-channels of delignified sugarcane bagasse (DSB), the mechanism of which was understood through FTIR and XPS spectroscopic studies. DSB, due to its porous morphology and abundant hydroxyl groups, shows remediation capabilities of methylene blue (MB) dye through physio-sorption but shows a low adsorption capacity of 80.
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