Publications by authors named "Murugesan Pavithra"
Nosocomial Candida colonization causes Systemic candidiasis in human with invasive infections in immunocompromised patients. Of all Candida spp., C.
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- Purkinje cells in the cerebellum are crucial for integrating sensory information with motor signals to fine-tune movement control based on behavioral and environmental demands.* -
- New research shows that climbing fibres transmitting sensory information to Purkinje cells can convey multiple types of sensory data and are influenced by previous activity levels, suggesting a complex networking of sensory input.* -
- The study found that individual Purkinje cells tend to receive inputs from different sensory modalities, with variations in climbing fibre responses based on their recent activity, indicating a need for adaptability in motor function.*
Absence epilepsy is characterized by the occurrence of generalized spike and wave discharges (GSWDs) in electrocorticographical (ECoG) recordings representing oscillatory activity in thalamocortical networks. The oscillatory nature of GSWDs has been shown to be reflected in the simple spike activity of cerebellar Purkinje cells and in the activity of their target neurons in the cerebellar nuclei, but it is unclear to what extent complex spike activity is implicated in generalized epilepsy. Purkinje cell complex spike firing is elicited by climbing fiber activation and reflects action potential firing in the inferior olive.
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