Publications by authors named "Murugesan H"

Introduction: Trepidation towards dental procedures is commonly seen in the adult population and is one of the major reasons for avoiding dental treatments.

Aim: To evaluate and compare the anesthetic potential of anterior middle superior alveolar (AMSA) nerve block versus local infiltration during crown lengthening in the maxilla, using a pain assessment tool.

Materials And Methods: Outpatients visiting the Department of Periodontics at Mahe Institute of Dental Sciences and Hospital were selected for the study.

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  • Parry-Romberg syndrome is a rare condition that leads to progressive shrinkage of one side of the face, with significant effects on a person's appearance and mental health.
  • The case report discusses a 14-year-old girl with a history of linear morphea who experienced seizures and was ultimately diagnosed with Parry-Romberg syndrome.
  • It emphasizes the importance of a coordinated approach among different specialists, including rheumatologists, dermatologists, neurologists, and ophthalmologists, in the comprehensive management of the syndrome.
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BACKGROUNDSubnational TB estimates are crucial for making informed decisions to tailor TB control activities to local TB epidemiology.METHODSA cross-sectional survey was conducted among 143,005 individuals in Tamil Nadu, India. Participants were screened for symptoms and underwent chest X-ray (CXR).

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Introduction And Purpose: Ensuring proper femoral component alignment post-Total Knee Arthroplasty (TKA) is crucial for normal patellofemoral (PF) kinematics. However, the customary 3° external rotation relative to the Posterior Condylar Axis (PC Axis) may not universally apply, and the expected final femoral component rotation remains unclear in functionally aligned knees. This study examines the relation between the Transepicondylar Axis (TEA) and PC axis, known as Posterior Condylar Angle (PCA) in Indian patients along with factors influencing PCA, and the feasibility of reproducing patient-specific PCA using image-guided Cuvis joint robot.

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Background And Objectives: Genetic factors are reported to be connected with tuberculosis (TB) infection. Studies have shown that genetic variations in genes involved in the vitamin D pathway influence the levels of vitamin D found in the bloodstream (serum). Cyp27b1 (1α-hydroxylase) is an enzyme that activates the synthesis of bioactive vitamin D by hydroxylation of 25(OH)DThe in vitro studies reported rare gene variants of Cyp27b1 such as rs118204011 and rs118204012, associated with loss of Cyp27b1 function and lower serum vitamin D levels.

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Estimating the burden of TB at the subnational level is critical to planning and prioritizing resources for TB control activities according to the local epidemiological situation. We report the experiences and operational challenges of implementing a TB prevalence survey at the subnational level in India. Information was collected from research reports that gathered data from periodic meetings, informal discussions with study teams, letters of communication, and various site visit reports.

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  • * Analysis of RNA sequencing data reveals that CENPA is significantly overexpressed in both PCa and metastatic PCa, particularly in cancer stem cells that are androgen receptor negative.
  • * Higher levels of CENPA correlate with advanced disease features, like nodal metastasis, and are associated with worse disease-free survival for patients.
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Aim: This survey was conducted to evaluate COVID-19 vaccination status in patients with autoimmune rheumatic diseases (AIRDs). Our objectives were to study vaccine hesitancy, adverse effects, breakthrough infections and flare of underlying disease in this population subgroup.

Methods: This was a multi-center, cross-sectional, interview-based survey done at 6 tertiary care centers across Tamil Nadu, in the southern part of India from September 15, 2021 to October 14, 2021.

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Several systemic anti-inflammatory and immunomodulatory agents were tried in the management of hyper inflammatory manifestations of COVID 19. JAK inhibitors have been widely deployed in rheumatology due to their benefits in managing uncontrolled inflammation. Tofacitinib is one of the most widely studied immunomodulators in rheumatology.

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Emergency pain management in symptomatic irreversible pulpitis commonly includes use of nonnarcotic analgesics. Acupuncture has been used in dentistry to alleviate pain after tooth extraction. The aim of this randomized, double-blind, placebo controlled clinical trial was to evaluate and compare the efficacy of acupuncture therapy and ibuprofen for pain management in such patients.

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