Publications by authors named "Murugan Mannangatti"
Article Synopsis
- The study investigates the effects of AC chemotherapy (Adriamycin and Cytoxan) on antioxidant enzymes and blood-related parameters in breast cancer patients.
- It involved 40 patients, with data collected before and after three cycles of treatment, using spectrophotometric techniques to measure enzyme levels.
- Results indicated a significant decrease in antioxidant enzymes and hematological parameters after treatment, suggesting that AC chemotherapy causes notable alterations in the body's oxidant/antioxidant balance.
It is of interest to evaluate the influence of breast cancer on oxidative stress, liver function tests, renal biomarkers, action of doxorubicin, cyclophosphamide and paclitaxel (AC-T) in the treatment and mechanism over altering the measured markers in breast cancer. Sixty histopathological confirmed cases of female patients suffering with breast carcinoma from the Department of Oncology at Omega Cancer Hospital, Visakhapatnam were included in the study. The investigation was performed in 3 groups: a control group containing 30 healthy females of similar age, 30 breast cancer patients without treatment and 30 patients receiving treatment with anticancer combination drugs AC-T.
View Article and Find Full Text PDFThe present study has been designed to evaluate urinary nephrin that best predicts the occurrence of renal dysfunction in type 2 diabetes mellitus patients and its correlation with clinical parameters of nephropathy. A total of 80 type 2 diabetes mellitus and 40 age- and gender-matched healthy controls were recruited. Biochemical and clinical parameters were analyzed in all the study participants.
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