Factors associated with major depressive disorder occurring after the onset of obsessive-compulsive disorder.

Background: We aimed to investigate the correlates of major depressive disorder (MDD) occurring after the onset of obsessive-compulsive disorder (OCD).

Methods: Forty-three OCD patients who developed MDD after the onset of OCD (OCD-MDD group) and 67 OCD patients without MDD (non-MDD, NMDD group) were compared with regard to sociodemographic characteristics, clinical history, symptom severity, types of obsessions and compulsions, insight degree, comorbid axis I and axis II diagnosis and quality-of-life level.

Results: The OCD-MDD group scored significantly higher on measures of obsessions, compulsions and depression severity than did the NMDD.