Risk of cataract among subjects with acquired immune deficiency syndrome free of ocular opportunistic infections.

Purpose: To evaluate the risk of cataract in the setting of AIDS.

Design: Prospective cohort study.

Participants: Subjects with AIDS free of ocular opportunistic infections throughout catamnesis.

Risk of cataract in persons with cytomegalovirus retinitis and the acquired immune deficiency syndrome.

Objective: To evaluate cataract risk in eyes of patients with AIDS and cytomegalovirus (CMV) retinitis and to identify risk factors.

Design: Prospective cohort study.

Participants: Patients with AIDS and CMV retinitis.

Practical management of patients with non-small-cell lung cancer treated with gefitinib.

Purpose: The use of gefitinib, the first drug approved to inhibit the epidermal growth factor receptor tyrosine kinase, is indicated in patients with non-small-cell lung cancer with tumors progressive after chemotherapy. The unique mechanism of action of this agent leads to distinctive patterns of response and toxicity in persons with lung cancer. Many of the principles of management relevant to gefitinib are distinct from those with conventional cytotoxic drugs.

Ocular presentation of primary central nervous system lymphoma: diagnosis and treatment.

Primary ocular lymphoma (POL), a lymphoma of the globe, is a restricted form of primary central nervous system lymphoma (PCNSL) that often progresses to the brain and meninges; frequently it is misdiagnosed until central nervous system (CNS) lymphoma develops. The optimal treatment has not yet been identified. We retrospectively reviewed the course and the treatment of POL in 31 patients.