Candida tropicalis morphotypes show altered cellular structure and gene expression pre- and post-exposure to fluconazole.

A feature of Candida tropicalis is its ability to undergo phenotypic switching that can affect antifungal sensitivity and virulence traits. Here, we investigated the effect of switching on alterations at the cellular structure level of C. tropicalis morphotypes and whether exposure to fluconazole (FLC) in vitro could be associated with these alterations in a morphotype-dependent manner.

Interfacial adaptation of NeoMTA Plus, BioRoot RCS and MTA in root-end cavities: A micro-CT study.

Aim: This study aimed to use the micro-computed tomography to evaluate the interfacial adaptation and the presence of gaps of NeoMTA Plus, BioRoot RCS, and MTA in the root-end cavities.

Methodology: Thirty standardized bovine roots measuring 15 mm in length were selected. Chemical-mechanical preparation was performed up to instrument #80 and obturation with the cold lateral compaction technique with cement based on zinc oxide and eugenol.

We need to talk about Candida tropicalis: Virulence factors and survival mechanisms.

Candida tropicalis is a notable species of the Candida genus representing an impressive epidemiology in tropical regions, especially in South America and Asia, where India already presents the species as the first in Candida epidemiology. Candida tropicalis has also shown a worrying antifungal resistance profile in recent years. It is essential to highlight that each pathogenic species of the Candida genus has a particular biology; however, Candida virulence factors are almost entirely based on studies with C.

Adhesion and biofilm formation by the opportunistic pathogen : what do we know?

 is among the most important  species in terms of epidemiology, virulence and resistance. Considering the increase in incidence and high rates of mortality associated with this species, knowledge of its adhesion and biofilm formation abilities is needed. These traits determine the persistence and survival of yeast on different indwelling medical devices and host sites.

Deciphering Colonies of Phenotypic Switching-Derived Morphotypes of the Pathogenic Yeast Candida tropicalis.

Background: Phenotypic switching generates fungal colonies with altered morphology and allows pathogens to adapt to changing environments.

Objective: This study investigated the structure and genetic factors of switched morphotypes colonies in Candida tropicalis.

Methods: Morphotypes of C.

Behavioural and electroencephalographic effects of systemic injections of 8-OH-DPAT in the pigeon (Columba livia).

The effects of systemic injections of the 5HT(1A) receptor agonist 8-OH-DPAT on the spontaneous ingestive, maintenance, locomotor and sleep-like behaviours, and the sleep/waking-related hippocampal electrographic activity were investigated in pigeons. 8-OH-DPAT (0.06, 0.

Behavioral and metabolic effects of central injections of orexins/hypocretins in pigeons (Columba livia).

In the present study, the acute behavioral and ingestive effects of ICV injections of mammalian orexin-A (ORXA; vehicle, 0.2, 0.6 or 2 nmol) and of orexin-B (ORXB; vehicle, 0.