Publications by authors named "Murilo Daher"

 To evaluate the correlation between a radiographic scale of lumbar degenerative disease and the Oswestry Disability Index (ODI).  A cross-sectional study in which the ODI quality of life questionnaire and the radiographic parameters for the classification of lumbar degenerative disease into different grades were compared to try to establish a relationship between them.  The relationship between the radiographic parameters and quality of life indicators does not behave homogeneously, considering the different grades of the lumbar grading scale.

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Scoliosis is the most prevalent type of spinal deformity, with a 2-3% prevalence in the general population. Moreover, surgery for scoliotic deformity may result in severe blood loss and, consequently, the need for blood transfusions, thereby increasing surgical morbidity and the rate of complications. Several antifibrinolytic drugs, such as tranexamic acid, have been regarded as safe and effective options for reducing blood loss.

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Study Design: Retrospective review of multicentric data.

Objectives: To estimate the time from initial visit to surgery in adolescent idiopathic scoliosis (AIS) patients and the main reasons for the time to surgery in a multicenter study.

Methods: This retrospective study evaluated 509 patients with AIS from 16 hospitals across six Latin American countries.

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Idiopathic hypertrophic pachymeningitis is rare cause of neurological symptoms with myelopathy due to spinal cord compression. We report a case of pachymeningitis, which was manifested primarily by tetraparesis after low-energy trauma and recurrence the myelopathy symptoms after 5 years of surgery. The patient, a 19-year-old woman, was subjected to extensive investigation without evidence of any underlying disease.

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Introduction: Among the interbody fusions, lateral lumbar interbody fusion allows access to the lumbar spine through the major psoas muscle, which offers several advantages to the spine surgeon. However, some of its drawbacks cause surgeons to avoid using it as a daily practice. Therefore, to address some of these challenges, we propose the prone transpsoas technique, differing mainly from the traditional technique on patient position-moving from lateral to prone decubitus, theoretically enhancing the lordosis and impacting the psoas morphology.

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Study Design: Multicentric retrospective study, Level of evidence III.

Objective: The objective of this multicentric study was to analyze the prevalence and risk factors of early postoperative complications in adult spinal deformity patients treated with fusion. Additionally, we studied the impact of complications on unplanned readmission and hospital length of stay.

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Article Synopsis
  • A study was conducted to find out how often incidental findings appear on MRI scans of the spine in children and teens under 18 years old.
  • The study analyzed 190 MRI exams, revealing that 21.05% of cervical, 13.83% of thoracic, and 22.63% of lumbar scans showed incidental findings, with various issues like disc herniations and curvature corrections identified.
  • The research concluded that while these incidental findings are less frequent in kids compared to adults, it's important for doctors to carefully assess the relationship between symptoms and what the MRIs show.
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Article Synopsis
  • Disc degeneration affects the intervertebral discs, potentially leading to conditions like herniation and stenosis, with genetic factors playing a larger role than environmental ones.
  • A narrative review of recent literature identifies several genes linked to disc degeneration, including those related to collagen and other proteins.
  • The review highlights advancements in understanding the genetic mechanisms behind disc degeneration, focusing on gene associations, single-nucleotide polymorphisms, and genetic-environmental interactions.
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Posttraumatic injury pain is commonly treated with oral nonsteroidal anti-inflammatory drugs. However, oral nonsteroidal anti-inflammatory drugs cause several adverse events, with topical formulations arising as an important alternative. Therefore, we aimed at evaluating the efficacy and safety of loxoprofen patch (LX-P) in the treatment of patients with posttraumatic pain.

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Objective: with increasing life expectancy around the world, fractures due to osteoporosis have become more common and the expenditure for treating them has also increased. The aim here was to evaluate the improvement in pain and quality of life among patients with compressive osteoporotic vertebral fractures undergoing vertebroplasty.

Methods: eighteen patients with 27 fractured vertebrae underwent vertebroplasty and were evaluated using the Oswestry 2.

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Introduction: Odontoid diameter in some individuals may not be large enough to accommodate two 3.5-mm cortical screws for anterior odontoid fracture fixation. The study was performed to evaluate, in a Brazilian population, the diameter of the odontoid process and the feasibility of using two 3.

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Objective: To compare heart rate variability in normotensive and hypertensive individuals and to observe the behavior of the autonomic nervous system after treatment with angiotensin II-converting enzyme inhibitors.

Method: The study comprised 286 patients diagnosed with arterial hypertension (AH) for the first time and divided into 4 groups according to diastolic blood pressure (DBP) levels: group A -- DBP<90 mmHg; group B -- DBP 90-99 mmHg; group C -- DBP 100-109 mmHg; group D -- DBP>110 mmHg. Group A (110 healthy individuals) and group C (79 patients with moderate AH) underwent 24-hour Holter-ECG with analysis of heart rate variability in time domain (TD) and frequency domain (FD).

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