Publications by authors named "Muriel Salvat"
Article Synopsis
- The study evaluated the CardioMEMS™ HF System in 103 French patients to assess its feasibility, safety, and clinical benefits post-implantation.
- Over two years, no device-related complications were reported, and the system showed a 50% reduction in heart failure hospitalizations compared to the year before implantation.
- Additionally, patients experienced lower pulmonary artery pressures and improvements in their functional class and overall quality of life.
Article Synopsis
- The study investigates the use of salt substitutes (saltSubs) for managing sodium intake in patients with chronic heart failure (CHF) in France, focusing on healthcare professional (HCP) recommendations and patient consumption.
- Only 13% of HCPs recommended saltSubs, while 17% of patients and 22% of caregivers reported using them, with those recommended showing a recent hospitalization for acute heart failure.
- The findings revealed that patients advised to use saltSubs were less likely to follow guideline-directed medical therapies (GDMTs), particularly angiotensin-converting enzyme inhibitors and related medications, indicating a potential conflict between saltSubs and standard CHF treatments.
The management of anxiety because of upcoming invasive coronary angiography (ICA) remains suboptimal. Previously published studies investigating the potential of virtual reality (VR) for the reduction of anxiety in ICA procedures used a subjective evaluation method. The purpose of this study was to determine whether the use of a VR program before ICA objectively decreases anxiety as assessed by the SD of normal to normal (SDNN).
View Article and Find Full Text PDFObjective: To determine whether changes in pulmonary vascular resistance (PVR) and changes in pulmonary artery compliance ( ) are associated with changes in exercise capacity assessed either by changes in peak oxygen consumption (' ) or by changes in 6-min walk distance (6MWD) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing balloon pulmonary angioplasty (BPA).
Methods: Invasive haemodynamic parameters, peak ' and 6MWD were measured within 24 h, before and after BPA (interval 3.1±2.
Article Synopsis
- Heart failure (HF) registries often have incomplete follow-up data, while medicoadministrative databases contain reliable long-term data but provide less clinical detail, making their combination beneficial yet largely untested.
- A study aimed to evaluate the effectiveness of linking the FRESH HF registry with the French National Healthcare System database (SNDS) using a probabilistic algorithm to enhance data accuracy.
- Results indicated that a majority of patients could be matched (94.3% accuracy for deaths) and highlighted discrepancies in data between the two systems, such as higher hospitalization rates in the SNDS compared to the registry cohort.*
Sequencing and titrating approach of therapy in heart failure with reduced ejection fraction following the 2021 European Society of Cardiology guidelines: an international cardiology survey.
Eur J Heart Fail
February 2023
Article Synopsis
- Recent guidelines suggest starting four key heart failure (HF) medications for patients with reduced ejection fraction (HFrEF) at once, but there's uncertainty about how cardiologists view this approach compared to HF specialists.
- A survey with 615 cardiologists globally revealed that most prefer a traditional sequential treatment method, starting with ACE inhibitors or other recommended therapies.
- Although many agree that beginning all four medications during initial hospitalization is doable, there's still a preference for the classic approach, indicating a need for research to alter treatment practices.
Background: Adaptive servo-ventilation (ASV) effectively suppresses central sleep apnoea (CSA) but has been associated with increased all-cause and cardiovascular mortality in chronic heart failure patients with reduced ventricular ejection fraction (HFrEF). All-cause and, especially, cardiovascular mortality in chronic heart failure is highly correlated with sympathetic tone. This analysis of SERVE-HF data investigated the effect of ASV on sympathetic tone in patients with HFrEF and CSA.
View Article and Find Full Text PDFExcessive ventilation (V̇E) during exercise, ascribed to heightened neural ventilatory drive and/or to increased "wasted" ventilation, is a feature of chronic thromboembolic pulmonary hypertension (CTEPH). In selected CTEPH patients, balloon pulmonary angioplasty (BPA) allows near-normalization of resting haemodynamic parameters but does not allow excess exercise hyperventilation to normalize. Neural ventilatory drive can be estimated by studying how arterial PCO (PaCO), end-tidal PCO (PETCO), V̇E and CO output (V̇CO) change across the exercise-to-recovery transition during a cardiopulmonary exercise test.
View Article and Find Full Text PDFBackground: Excessive ventilation (V̇E) and abnormal gas exchange during exercise are features of chronic thromboembolic pulmonary hypertension (CTEPH). In selected CTEPH patients, balloon pulmonary angioplasty (BPA) improves symptoms and exercise capacity. How BPA affects exercise hyperventilation and gas exchange is poorly understood.
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- * There is a need for more research on the effectiveness of influenza and pneumococcal vaccines, as well as the COVID-19 vaccine, in preventing heart-related issues in HF patients; current guidelines recommend annual vaccinations.
- * To enhance vaccination rates among HF patients, a coordinated health policy involving various healthcare professionals is necessary, as implementation of existing vaccination recommendations has been lacking.
Aims: Hospitalization for acute heart failure (HF) is followed by a vulnerable time with increased risk of readmission or death, thus requiring particular attention after discharge. In this study, we examined the impact of intensive, early follow-up among patients at high readmission risk at discharge after treatment for acute HF.
Methods And Results: Hospitalized acute HF patients were included with at least one of the following: previous acute HF < 6 months, systolic blood pressure ≤ 110 mmHg, creatininaemia ≥ 180 µmol/L, or B-type natriuretic peptide ≥ 350 pg/mL or N-terminal pro B-type natriuretic peptide ≥ 2200 pg/mL.
A 52-year-old man with acute peritonitis developed severely decreased left ventricular (LV) ejection fraction. Multimodal imaging allowed the diagnosis of sepsis-related myocardial calcification. Moreover, 2-dimensional speckle tracking echocardiography allowed a better understanding of LV dysfunction and confirmed the hypothesis that regional LV dysfunction is in accordance with the localization of calcifications.
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- Acute heart failure (AHF) is a serious condition that causes about 5% of emergency hospital admissions in Europe, with the study involving 793 patients, mostly men around 72 years old.
- Many patients experienced symptoms like dyspnea and lower limb edema before seeking help, with about half showing symptoms for over 15 days prior to hospitalization.
- Referral methods varied, with emergency services often called during acute symptoms, while cardiologists were typically consulted for longer-standing issues; the study recommends enhancing AHF treatment networks in the French healthcare system for better patient care.
Background: Atherosclerosis is associated with a worse prognosis in many diseases such as ischemic cardiomyopathy, but its impact in non-ischemic dilated cardiomyopathy (dCMP) is lesser known. Our aim was to study the prognostic impact of coronary atherosclerotic burden (CAB) in patients with dCMP.
Methods: Consecutive patients with dCMP and left ventricular (LV) dysfunction diagnosed by concomitant analysis of invasive coronary angiography (ICA) and CMR imaging were identified from registry-database.
Aims: The objective of this study was to determine the accuracy of right ventricular function (RVF) assessed by Cadmium Zinc Telluride ECG-gated SPECT equilibrium radionuclide angiocardiography (CZT-ERNA).
Methods And Results: Twenty-one consecutive patients with cardiomyopathy (aged 54 ± 19 years; 62% male) were included. RV ejection fraction (EF) and volumes were analyzed by CZT-ERNA and compared with values obtained by cardiac magnetic resonance imaging (CMR).
Aims: The aim was to assess the effect of a telemonitoring programme vs. standard care (SC) in preventing all-cause deaths or unplanned hospitalisations in heart failure (HF) at 18 months.
Methods And Results: OSICAT was a randomised, multicentre, open-label French study in 937 patients hospitalised for acute HF ≤12 months before inclusion.
Background: Despite clinical optimization, many chronic heart failure (CHF) patients remain symptomatic with dyspnea and poor quality of life.
Study Objective: While oxygen therapy is prescribed in severe cases, the actual prevalence of different patterns of hypoxemia is unknown.
Methods: We analyzed 183 stable CHF patients with optimized medical treatment in the "MARS" database.
Pulmonary hypertension (PH) is a common and severe complication of heart failure (HF). Consequently, HF is the leading cause of PH. For many years, specialists have attempted to better understand the pathophysiology of PH in HF, to define its prevalence and its impact on prognosis in order to improve the therapeutic management of these patients.
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