Publications by authors named "Muriel Bouton"
Article Synopsis
- The French health authorities established guidelines for "good transfusion practices," but there is limited guidance for managing transfusions in patients who have undergone allogeneic hematopoietic stem transplantation (allo-HCT).
- A workshop aimed to standardize transfusion practices for this patient group where recommendations are lacking.
- Key recommendations include conducting extended blood cell phenotyping before transplantation, monitoring antibody levels, and assessing chimerism at specific intervals post-transplant to adjust transfusion strategies as needed.
Immunization against the platelet αIIbβ3 glycoprotein due to blood transfusion represents one of the most severe complications in Glanzmann thrombasthenia (GT) disease. Anti-αIIbβ3 isoantibodies development may lead to ineffective platelet transfusion and can, in case of pregnancy, cross the placenta leading to fetal thrombocytopenia. We describe here the case of a girl with type I GT who developed high rates of anti-αIIbβ3 isoantibodies after first and unique blood transfusion.
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