This study focused on searching for more effective nanomaterials for environmental remediation and health protection; thus, coliform bacteria, yeast and the organic food dye sunset yellow were selected as target pollutants to be eliminated under solar light by Ag/Cr-TiO and Pd/Cr-TiO. Firstly, Cr was in situ incorporated into the anatase crystalline lattice by the sol-gel method; then, Ag or Pd nanoparticles were deposited on Cr-TiO by chemical photoreduction. The scientific challenge addressed by the development of these composites was to analyse the recovery of Cr, to be employed in photocatalyst formulation and the enhancement of the TiO photocatalytic activity by addition of other noble metals.
View Article and Find Full Text PDFBackground: The use of tools that allow estimation of the probability of progression of chronic kidney disease (CKD) to advanced stages has not yet achieved significant practical importance in clinical setting. This study aimed to develop and validate a machine learning-based model for predicting the need for renal replacement therapy (RRT) and disease progression for patients with stage 3-5 CKD.
Methods: This was a retrospective, closed cohort, observational study.
Introduction: Bipolar disorder (BD) is a chronically progressive mental condition, associated with a reduced quality of life and greater disability. Patient admissions are preventable events with a considerable impact on global functioning and social adjustment. While machine learning (ML) approaches have proven prediction ability in other diseases, little is known about their utility to predict patient admissions in this pathology.
View Article and Find Full Text PDFIn this work, photocatalytic materials constituted by Cr-doped TiO (Cr-TiO) decorated with noble metals show high effectiveness in the mineralization of Acid Orange 7 (AO7) and in the disinfection of real river water. The materials were firstly obtained by sol-gel method to get Cr-TiO that was subsequently modified by photochemical deposition of Ag or Pd nanoparticles (Ag/Cr-TiO, Pd/Cr-TiO). Chemical-physical characterization results evidenced that the noble metals were homogeneously distributed on the Cr-TiO surface.
View Article and Find Full Text PDFChemical reagents have become fundamental products in daily life use, they contribute in several ways to establish a high level of social development. In the case of higher education, the use of reagents allows learning thought laboratory practices. These practices must be carried out under preventative measures, in order to avoid negative impacts on the environment and human health; this generates the need to identify and classify the chemical substances used and the waste generated.
View Article and Find Full Text PDFPinna nobilis is undergoing one of the most dramatic events suffered by an endangered species. An emerging disease has relegated its populations to coastal lagoons or estuaries with salinities beyond the 36.5-39.
View Article and Find Full Text PDFBackground: Procalcitonin (PCT) and C-Reactive Protein (CRP) are useful biomarkers to differentiate bacterial from viral or fungal infections, although the association between them and co-infection or mortality in COVID-19 remains unclear.
Methods: The study represents a retrospective cohort study of patients admitted for COVID-19 pneumonia to 84 ICUs from ten countries between (March 2020-January 2021). Primary outcome was to determine whether PCT or CRP at admission could predict community-acquired bacterial respiratory co-infection (BC) and its added clinical value by determining the best discriminating cut-off values.
Background: It is unclear whether the changes in critical care throughout the pandemic have improved the outcomes in coronavirus disease 2019 (COVID-19) patients admitted to the intensive care units (ICUs).
Methods: We conducted a retrospective cohort study in adults with COVID-19 pneumonia admitted to 73 ICUs from Spain, Andorra and Ireland between February 2020 and March 2021. The first wave corresponded with the period from February 2020 to June 2020, whereas the second/third waves occurred from July 2020 to March 2021.
A recent genome-wide association study (GWAS) of 59 cerebrospinal fluid (CSF) proteins with a connection to Alzheimer's disease (AD) demonstrated an association between increased levels of chemokine ligand 2 (CCL2) with an atypical chemokine receptor chemokine-binding protein 2 variant V41A (ACKR2-V41A; rs2228467). High levels of CCL2 are associated with increased risk of AD development as well as other inflammatory diseases. In this study we characterized the biological function of the ACKR2-V41A receptor compared to the wild type allele by measuring its ligand binding affinity, CCL2 scavenging efficiency, and cell activation sensitivity.
View Article and Find Full Text PDFBackground: Evaluating severity of illness of patients with prolonged mechanical ventilation (PMV) is important to adopt the best appropriate care management for each individual. Yet, no severity-of-illness scoring system has been specifically designed for this type of patients. The aim of this study was to develop and validate a new instrument, the Multi-INdependence Dimensions (MIND) questionnaire designed to comprehensively measure the severity of illness of patients under PMV.
View Article and Find Full Text PDFIn this study, titanium dioxide powder obtained by the sol-gel method and TiO₂ nanotubes, were prepared. In order to increase the TiO₂ photoactivity, the powders and nanotubes obtained were modified by dye sensitization treatment during the oxide synthesis. The sensitizers applied were Quinizarin (Q) and Zinc protoporphyrin (P).
View Article and Find Full Text PDFObjective: The mesoportal shunt (MPS) and liver transplantation (LT) have changed the scenario of extrahepatic portal vein obstruction (EHPVO) since the MPS, the only "curative" technique, can now be offered in asymptomatic patients and also thrombotic complications of LT have increased the incidence of EHPVO.
Material And Methods: A retrospective study of patients undergoing surgery for EHPVO was conducted between 1990 and 2015. An analysis was done for the shunt permeability and clinical evolution over time.
Aim: To analyze the benefits of Split (for adult and for child) in liver transplantation.
Patient/methods: 1) Analysis of the waiting list mortality estimated on 228 inclusions for transplant since January 2004 to December 2008.2) Impact of the variant techniques (living-related donor and split) on the waiting list mortality in our patients.
Eur J Pediatr Surg
January 2011
Aim: Aim of the study was assess the results of the treatment of High-Risk Hepatoblastoma (HRH) in a tertiary center where all liver surgery facilities, including pediatric transplantation (LT), are available.
Methods: 91 primary liver tumors treated between 1991 and 2009 were retrospectively reviewed. HRHs as defined by the SIOP criteria (PRETEXT IV or any stage with venous involvement, extrahepatic disease, tumor rupture and <100 ng/ml serum AFP) were identified and imaging and biopsies were reviewed.
Background: Barthel Index (BI) measures functional status. Our aim was to analyze if BI and other factors not included in Pneumonia Severity Index (PSI) predict mortality in general population with community acquired pneumonia (CAP).
Methods: Prospective observational study including all patients with CAP diagnosed in 2006.
Objective: To analyze the evolution of Small Bowel Transplantation program since the beginning of the program.
Material And Methods: [corrected] All children who underwent intestinal transplantation between 1997 and 2009 were retrospectively reviewed: epidemiological data, status before transplant, surgical technique, immunosupression, results, survival and long.term quality of life were analysed.
Aim: Liver pediatric transplantation finds in the lack of donors its main limitation. An alternative in those cases is split liver grafts from bigger donors.
Patients And Method: We performed a retrospective study of 56 hepatic split transplants performed between 1994 and 2007.
Aim: Even though Spain has the highest donation rate in the world, our needs cannot be satisfied, specially in younger children. Living-related donor transplant is an alternative in those cases.
Patients And Method: We performed a retrospective study of 57 living-related donor transplants performed in our hospital between June 1993 and December 2007.
To evaluate in routine hospital practice the clinical response to ertapenem in comparison with other parenteral antibiotics in the treatment of community-acquired pneumonia (CAP), clinical records from patients with severe CAP treated with ertapenem from July 2002 to June 2006 in seven Spanish hospitals were retrospectively reviewed. Patients were classified according to the Pneumonia Severity Index (PSI). Each ertapenem-treated patient was matched with two patients in the same hospital treated with other antibiotics, according to age (difference
Enferm Infecc Microbiol Clin
April 2009
Objective: The objective of this study was to determine the prevalence and genotype distribution of chronic hepatitis C virus (HCV) infection in a penitentiary population. The secondary objective was to describe histological findings in liver of the biopsied population, and identify risk factors associated with liver fibrosis and inflammatory activity.
Methods: Among 800 inmates, 730 accepted HCV antibody screening and PCR confirmation.
Eur J Pediatr Surg
December 2008
Introduction: Several variant techniques have been developed as alternatives to whole liver transplantation to improve size matching, timing, or simply to increase the pool of donors. The aim of this study was to assess the requirements of these techniques and their outcomes in a pediatric transplant program.
Patients And Method: A retrospective analysis of children on the waiting list in the last 4 years was carried out.
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