[Tissue engineering in urology, new approaches for urinary bladder reconstruction].

Tissue engineering as applied to urologic pathology is covered extremely poor in the literature despite recently gaining popularity of regenerative medicine. The review reflects the current problems associated with reconstructive surgery of the urinary bladder, experience of the researchers from the United States in implementing cellular technologies for bladder replacement, the problems and prospects of this direction in case of such a severe pathology, as fibrous transformated bladder.

[Role of supravesicular urine diversion in the treatment of patients with renal and urethral tuberculosis].

The article presents the results of the survey, etiopathogenetic and surgery treatment of 73 patients with nephrotuberculosis complicated by tuberculous ureteritis. Patients were divided into 4 groups. 1-3 Groups of patients underwent urine diversion by percutaneous puncture nephrostomy, open nephrostomy and internal stent placement.

[Role of protein kinases of human red cell membrane in deformability and aggregation changes].

The proteomic analysis has showed that red cell membrane contains several kinases and phosphatases. Therefore the aim of this study was to investigate the role of protein kinases of human red cell membrane in deformability and aggregation changes. Exposure of red blood cells (RBCs) to some chemical compounds led to change in the RBC microrheological properties.

[Changes of blood rheological properties and its correction under surgical and drug treatment in patients with phlegmons of maxillofacial area].

Blood theological properties in patients with phlegmons of maxillofacial area before treatment, immediately after surgical treatment and after surgical treatment combined with reamberin therapy were examined in the study. Negatively changed theological profile values somewhat improved after operation, mainly because of blood and serum viscosity decrease by 10-11% and blood transport capability enhancement. But significant positive macro- and microrheological changes was only received by surgical treatment combined with reamberin.

[Hemorheological properties of new xanthine derivative studied on model of streptozotocin induced diabetes mellitus].

Influence of a new xanthine derivative SUM-55 on microrheological properties erythrocytes in rats with experimental diabetes has been investigated. It is shown that compound SUM-55 significantly reduces aggregation and increases deformability of erythrocytes. Comparative analysis showed that SUM-55 is comparable with pentoxyphylline in the ability to reduce aggregation of erythrocytes and is superior to the reference drug in increasing deformability of red bloodcells.

[Techniques for experimental and clinical studies of erythrocyte deformability].

Deformability is an important property of red blood cells and ensures the efficiency of their transport in the microcirculatory vascular system, as well as tissue oxygenation. A study of erythrocyte deformability uses different methods: filtration through about 5.0-microm pores, laser difractometry techniques and a focus of attention has recently been on a procedure for measuring the deformability of erythrocytes in a flow microchamber.

[Surgical urinary and male genital tuberculosis].

A total of 209 and 188 patients with urogenital tuberculosis were operated on in 1985-1987 (Period 1) and in 2005-2007 (Period 2), respectively. The mean age of patients with nephrotuberculosis has increased by 10 years in the past 20 years. The total number of operations has retained as before: organ-removing operations have decreased from 61.

[Surgical treatment of nephrotuberculosis in the present-day epidemiological situation].

The article presents data on the structure of operative interventions and assessment of the role of an early kidney decompression in management of renal tuberculosis complicated by urethritis. It was found that such eradicative techniques as nephrectomy and nephruretherectomy still prevail. Early drainage of the kidney for its decompression allows preservation of the kidney and following reconstructive surgery in 70.

[Red blood cell aggredation: mechanisms, adrenergic regulation].

Red blood cell aggregation is a complex multiple-factor process and exerts a substantial effect on realization of basic blood function: oxygen transport. Insufficient knowledge about mechanisms of erythrocyte aggregation in normal conditions and, especially, in pathological conditions, complicates the control and correction of possible negative consequences of this process. On addition, red blood cell aggregation process is a suitable model for the elucidation of basic patterns of intercellular interactions.

[Rheological of blood and oxygen transport in long-term adaptation to muscular load].

The blood viscosity became reduced after a long-term muscular adaptation in dogs. The main adaptation mechanism is associated with an autoregulated haemodilution and improvement of the red blood cells' microrheology (deformities and aggregation). The findings suggest that reduction in the haemodilution and the blood oxygen capacity are accompanied by a heightened efficiency of the oxygen transport.

[Analysis of rheologic changes in blood based on a hemorheologic profile concept].

Changes in blood rheology were studied in 106 female hypertensive patients. Basic parameters of blood rheology were recorded: total blood viscosity, plasma viscosity, Hct, erythrocyte aggregation and deformability, fibrinogen, albumin/globulin ratio, and Hct/eta ratio. This set of parameters was presented as the hemorrheological profile.

[Hemorheological profiles in patients with arterial hypertension and bronchial asthma].

Hemorheological parameters were studied in patients with essential hypertension (men and women) and those with bronchial asthma. The rheological findings were established as a hemorheological profile. The latter is a set of macro- and microrheological parameters under various pathological conditions.