Publications by authors named "Murata A"

Fallopian tube carcinoma, presenting as an inguinal hernia, is a rare entity. We report the case of a woman in her 70s with a history of hysterectomy and right oophorectomy 29 years prior who presented with left cervical lymphadenopathy and elevated CA125 levels. Imaging revealed a tubular structure in the left pelvic region extending into the inguinal hernia sac.

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Abemaciclib, a cyclin-dependent kinase 4/6 inhibitor, is crucial in treating hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic or recurrent breast cancer. However, its association with drug-induced interstitial lung disease (DI-ILD) is concerning. We present an 82-year-old woman with breast cancer receiving abemaciclib, who developed persistent cough and malaise.

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  • Sleep apnea is common in patients with heart failure and can worsen their health outcomes; the study examines the effects of tofogliflozin, an SGLT2 inhibitor, on this condition.
  • In the study, tofogliflozin significantly lowered the apnea-hypopnea index (AHI) in patients after 6 months, indicating reduced severity of sleep apnea.
  • Improvements in body weight and water content were seen alongside the reduction in AHI, suggesting a possible link between decreased body water and sleep apnea severity, while cardiorenal functions remained unchanged.
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Background: The prevalence, characteristics, and prognosis of atrial functional mitral regurgitation (AFMR) based on severity remain unclear. No studies have systematically evaluated quantitative thresholds, such as effective regurgitant orifice area (EROA) or regurgitant volume, in relation to outcomes in AFMR. This multicenter study aimed to clarify the clinical implications of both qualitative and quantitative assessments of AFMR severity.

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Unlabelled: Primary cardiac lymphoma is an extremely rare disease, with the most common being diffuse large B-cell lymphoma (DLBCL). Fibrin-associated diffuse large B-cell lymphoma (FA-DLBCL) has been classified as a rare and unusual type of lymphoma and is included in the category of DLBCL associated with chronic inflammation (DLBCL-CI). In this study, we report a case of FA-DLBCL in the aortic valve and ascending aorta of a 51-year-old-woman.

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Introduction: Pedicle screws are commonly used in fixation to treat various spinal disorders. However, screw loosening is a prevalent complication, particularly in patients with osteoporosis. Various biomechanical studies have sought to address this issue, but the optimal depth and trajectory to increase the fixation strength of pedicle screws remain controversial.

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Sodium-glucose cotransporter 2 inhibitors have demonstrated positive effects in heart failure (HF) patients. However, the effects of dapagliflozin in patients with decompensated HF remain unclear. This study aimed to compare the efficacy and safety of early and late dapagliflozin administration for decompensated HF.

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Existing studies evaluating the comparison of clinical outcome of percutaneous coronary intervention (PCI) for severe calcified coronary lesions are limited, and the clinical outcomes of PCI for different morphologies of calcified lesions are controversial. Overall, consecutive 576 lesions with severe calcification that were treated with PCI from 2010 to 2021 at Nagoya Heart Center were investigated. All lesions were assessed using invasive coronary angiogram (CAG) or computed tomography-CAG at 12 months after DES implantation.

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  • Ultrasound measurements of quadriceps muscle thickness (QMT) can be effectively used to assess muscle mass in older heart failure patients, particularly those aged 65 and above.
  • *The study involved 595 hospitalized patients, where QMT was measured with high reliability, demonstrating excellent agreement between different observers.
  • *Findings indicate that lower height-adjusted QMT is linked to higher mortality rates, highlighting its potential as a prognostic tool in heart failure management.*
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Organic cation transporter 2 (OCT2/SLC22A2) is predominantly localized on the basolateral membranes of renal tubular epithelial cells and plays a crucial role in the renal secretion of various cationic drugs. Although variations in substrate selectivity among renal organic cation transport systems across species have been reported, the characteristics of OCT2 remain unclear. In this study, we demonstrated that atenolol, a β1-selective adrenergic antagonist, is transported almost exclusively by human OCT2, contrasting with OCT2s from other selected species.

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Sleep disordered breathing (SDB) is a common comorbidity in patients with atrial fibrillation (AF). Patients undergoing pulmonary vein isolation (PVI) for AF have a high prevalence of SDB. In previous studies, some patients with AF had Cheyne-Stokes respiration (CSR).

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  • * Doctors effectively treated her condition using percutaneous drainage, avoiding surgery and its potential complications.
  • * Follow-up CT scans showed complete recovery, emphasizing the success of minimally invasive treatments for elderly patients with complex abdominal issues.
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Own child's face is one of the most socially salient stimuli for parents, and a faster search for it than for other children's faces may help provide warmer and more sensitive care. However, it has not been experimentally examined whether parents find their child's face faster. In addition, although own child's face is specially processed, the search time for own child's face may be similar to that for other socially salient stimuli, such as own or spouse's faces.

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  • A novel handheld ultrasound device with AI-POCUS was tested in 200 patients across two hospitals in Japan to assess its ability to automatically measure left ventricular ejection fraction (LVEF).
  • The comparison of AI-POCUS results to standard ultrasound methods showed a strong correlation (ICC 0.81) and effective detection of reduced LVEF with 85% sensitivity and 81% specificity.
  • While AI-POCUS accurately assessed LVEF, it tended to underestimate left ventricular (LV) volumes, especially for larger LV sizes; however, an updated software version showed improved accuracy after leveraging larger and more varied data sets.
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Esophageal duplication cysts are rare congenital noncancerous growths. Symptoms of this disease are reported to be asymptomatic in approximately 70% but include respiratory symptoms such as coughing and difficulty breathing. Minimally invasive removal of these cysts without esophagectomy is typically recommended.

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  • Decreased cough strength in myasthenia gravis (MG) increases the risk of aspiration and crisis, prompting this study on cough peak flow (CPF) measurements in MG patients.
  • The study included 26 MG patients who independently measured their CPF, and the results were compared with pulmonary function tests and MG assessments before and after treatment.
  • The findings revealed a high reliability for CPF measurements, with a cut-off value of 205 L/min for aspiration risk, showing good sensitivity and specificity as a useful biomarker for assessing MG symptoms.
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Aim: Measurement of O-glycosylated middle hepatitis B surface antigen (HBsAg glycan isomer, HBsAgGi) has been developed to quantify hepatitis B virus (HBV) infectious virions and distinguish them from subviral particles. This study aimed to evaluate the association between serum HBsAg seroclearance and serum HBV virions measured by HBsAgGi in patients with chronic hepatitis B (CHB).

Methods: Serum HBsAgGi levels were quantified in 232 treatment-naïve patients with CHB genotype C.

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  • * Out of 77 participants, a majority successfully performed daily self-monitoring, though younger patients and those with more severe HF symptoms were less consistent.
  • * The findings suggest that self-telemonitoring is practical for older HF patients and may help in early detection of worsening conditions, potentially leading to better management and outcomes.
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Sandwich culture systems are techniques that cultivate cells by sandwiching them between the top and bottom substrates. Since the substrates can be separated, the system is expected to be applied to the construct layering of patterned cells and to the isolation of stacked cells. In this study, we prepared hydrogels composed of zwitterionic sulfabetaine polymers, poly[2-(2-(methacryloyloxyethyl)dimethylammonio)ethyl-1-sulfate] (PZBMA).

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  • The document in question addresses corrections made to the original article identified by DOI: 10.3389/fcvm.2023.1212882.
  • The corrections aim to address inaccuracies or errors found in the previously published research.
  • These revisions ensure the integrity and reliability of the findings presented in the article.
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We here report a new molecule DoNA binding to a CAG repeat RNA. DoNA is a dimer of the NA molecule that we previously reported. NA binds with high affinity to a CAG repeat DNA but not significantly to a CAG repeat RNA.

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  • * Abdominal CT scans revealed dilated blood vessels in the small intestine, leading to the diagnosis of a small intestinal arteriovenous malformation (AVM) after further endoscopic procedures.
  • * The AVM was successfully treated by clipping it through endoscopic techniques, which showed promising results and suggested that DBE could be a safe alternative to surgery for such cases.
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A woman in 70s was diagnosed with lung cancer, and a right atrial mass was discovered incidentally during preoperative examination by contrast-enhanced computed tomography (CT). Transesophageal echocardiography revealed a 20-mm, stemmed, spherical mass with low internal echogenicity and partially high echogenicity extending from the junction of the inferior vena cava to the posterior wall of the right atrium. Patent foramen ovale( PFO) was also confirmed.

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Purpose: The purpose was to assess the outcomes of medial patellofemoral ligament (MPFL) allograft reconstruction with or without tibial tubercle osteotomy (TTO) in adolescents, with a focus on evaluating demographic and imaging characteristics on outcomes.

Methods: A single-institution retrospective study was performed of patients ages 12 to 19 years who underwent MPFL reconstruction +/- TTO for the treatment of lateral patellar instability. Demographic, clinical, surgical, and postoperative information was collected.

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