The Effect of Three Different Local Cold Applications on Pain Severity, Anxiety Level, and Physiological Parameters in Intra-Articular Injections for Knee Osteoarthritis Treatment.

Minimizing pain and anxiety associated with intra-articular injection interventions is important for patient satisfaction and comfort. The sample of this quasi-experimental study consisted of 120 patients who received intra-articular knee injections for the first time. Patients were divided into four study groups before injection.