Comparison of sheep and goat preferences for different forms of stoned olive cake.

The objectives of this experiment were to investigate voluntary intake of stoned olive cake (SOC) in sheep and goats. The feeding experiment was carried out with a total of 10 animals consisting of five Karya yearlings and five Saanen goats (28.0 ± 2.

The effects of ration particle size and live yeast supplementation on dairy cows performance under heat stress conditions.

The objectives of this experiment were to evaluate the effects of ration particle size and dietary supplementation of live yeast (LY; Saccharomyces cerevisiae) on dry matter intake, milk yield and milk quality, apparent nutrient digestibility, ruminal fermentation parameters, and ruminal volatile fatty acids in dairy cattle under heat stress condition. Four multiparous Holstein dairy cattle in midlactation were fed 4 diets: high particle size (HPS), high particle size with 1 g/d/cow LY (Levucell® Sc 10 ME Titan® CNCM I-1077 (10 × 10 cfu/g) (HPS + LY), short particle size (SPS), short particle size with 1 g/d/cow LY (Levucell® Sc 10 ME Titan® CNCM I-1077 (10 × 10 cfu/g) (SPS + LY). Treatments were arranged in a 2 × 2 factorial within a 4 × 4 Latin square design.

GSH-Activated Light-Up Near-Infrared Fluorescent Probe with High Affinity to αβ Integrin for Precise Early Tumor Identification.

The development of tumor-associated, stimuli-driven, turn-on near-infrared (NIR) fluorophores requires urgent attention because of their potential in selective and precise tumor diagnosis. Herein, we describe a NIR fluorescent probe (CyA-cRGD) comprised of a fluorescence reporting unit (a cyanine dye) linked with a GSH-responsive unit (nitroazo aryl ether group) and a tumor-targeting unit (cRGD). The NIR fluorescence of CyA-cRGD with sensitive and selective response to GSH can act as a direct off-on signal reporter for GSH monitoring.

Near-infrared off-on fluorescence probe activated by NTR for in vivo hypoxia imaging.

Selective and efficient detection and imaging of nitroreductase (NTR) overexpressed in hypoxic tissues is of great importance for better understanding its biological functions. The effective optical probes equipped for NTR detection in vivo is still lacking, so we developed an innovative near infrared (NIR) fluorescent on-off probe (Cy-NO) composed of fluorescence reporting unit (an aminocyaine dye) and recognition unit (p-nitrobenzylcarbamate group). The response and mechanism of the NTR activated reduction of Cy-NO were evaluated in vitro through kinetic optical studies, mass spectra analysis and docking calculations.

Methionine-Decorated Near Infrared Fluorescent Probe for Prolonged Tumor Imaging.

Methionine (Met) is one of the essential amino acids of which the transport system L is overexpressed in various tumor cells. In this study, a near-infrared fluorescent dye (IR-780) and methionine were conjugated through a piperazin-polyamines linker to form Cy-Met. The successful synthesis of Cy-Met was validated by optical characterization, NMR, and MS spectra.

Biocompatible CuS-based nanoplatforms for efficient photothermal therapy and chemotherapy in vivo.

Near-infrared (NIR) photothermal therapy (PTT) is a new approach to ablate cancer without affecting normal tissues. A pivotal concern of PPT is to develop photo-responsive agents with high biocompatibility as well as effective photothermal conversion efficiency. Copper sulfide (CuS) nanoparticles prepared are characterized by their low synthesis cost, wide NIR absorption range, good biocompatibility and favorable NIR photothermal conversion efficiency.