Biological Augmentation With Retro-Drilling Core Decompression in Early Stage of Femoral Head Avascular Necrosis.

Osteonecrosis of the femoral head can lead to end-stage osteoarthritis when left untreated. The incidence has been on the rise since the onset of the COVID-19 pandemic. Core decompression of the femoral head is usually the first line of surgical treatment when conservative options fail.

A New Era for PET/CT: Applications in Non-Tumorous Renal Pathologies.

Non-tumorous kidney diseases include a variety of conditions affecting both the structure and function of the kidneys, thereby causing a range of health-related problems. Positron emission tomography/computed tomography (PET/CT) has emerged as a potential diagnostic tool, offering a multifaceted approach to evaluating non-tumorous kidney diseases. Its clinical significance extends beyond its conventional role in cancer imaging, enabling a comprehensive assessment of renal structure and function.

F-FDG PET/CT Imaging for Treatment Response Assessment of Cardiac Primitive Neuroectodermal Tumor.

Primitive neuroectodermal tumors (PNETs) are rare and aggressive members of the small round cell carcinoma family. Generally, PNETs are classified into two main groups: PNETs of the central nervous system and PNETs of the peripheral nervous system. Herein, we report the therapy response assessment of a rare case of isolated cardiac PNET using F-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) imaging.

Current barriers and recommendations on the diagnosis of transthyretin amyloid cardiomyopathy: a Delphi study.

Objectives: This study has been conducted to investigate the non-invasive diagnostic journey of patients with a transthyretin amyloid cardiomyopathy (aTTR-CM) in Turkey, identify the challenges and uncertainties encountered on the path to diagnosis from the perspectives of expert physicians, and develop recommendations that can be applied in such cases.

Methods: This study employed a three-round modified Delphi method and included 10 cardiologists and five nuclear medicine specialists. Two hematologists also shared their expert opinions on the survey results related to hematological tests during a final face-to-face discussion.

Minced Meniscus: Biologic Augmented Meniscal Implant Treatment.

Applications of meniscus scaffolds are crucial for preserving articular cartilage tissue, restoring normal joint mechanics, and stabilizing joints with partial meniscus deficits. Studies are still being conducted to determine how meniscus scaffold applications can create viable and durable tissue. The surgical procedure described in this study uses the meniscus scaffold and minced meniscus tissue.

Combined Autologous Adductor Magnus and Partial Quadriceps Tendon Technique for Medial Patellofemoral Ligament Reconstruction and Cellularized Scaffold Implantation of the Patella.

There are many studies in the literature on the use of adductor magnus and quadriceps tendons in primary or revision surgery of patellofemoral instability in skeletally immature patients. In this Technical Note, the combination of both tendons is presented with cellularized scaffold implantation cartilage surgery in the patella.

Joint EANM/SNMMI procedure guideline for the use of Lu-labeled PSMA-targeted radioligand-therapy (Lu-PSMA-RLT).

Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically significant prostate adenocarcinomas, and patients with target-positive disease can easily be identified by PSMA PET imaging. Promising results with PSMA-targeted radiopharmaceutical therapy have already been obtained in early-phase studies using various combinations of targeting molecules and radiolabels. Definitive evidence of the safety and efficacy of [Lu]Lu-PSMA-617 in combination with standard-of-care has been demonstrated in patients with metastatic castration-resistant prostate cancer, whose disease had progressed after or during at least one taxane regimen and at least one novel androgen-axis drug.

The adductor magnus tendon is a viable option for medial patellofemoral ligament reconstruction, but with a busy surrounding neurovascular topography.

Purpose: To describe the proximity of the neurovascular structures surrounding the adductor magnus (ADM), to delineate a safe boundary focusing on the techniques used during graft harvest and to evaluate whether the length of the ADM tendon is sufficient for safe medial patellofemoral ligament (MPFL) reconstruction.

Methods: Sixteen formalin-fixed cadavers were dissected. The area surrounding the ADM, the adductor tubercle (AT) and the adductor hiatus was exposed.

The Co-Use of Stromal Vascular Fraction and Bone Marrow Concentrate for Tendon Healing.

Objective: The Achilles tendon is the most frequently injured tendon in the human body, despite being the strongest. Many conventional treatments including medication, surgical interventions, and physical therapy are available, however, the desired results are often not achieved. Stromal vascular fraction (SVF) and bone marrow concentrate (BMC) are two additional cellular treatment options.

Which design tolerates rotational mismatch better in unicompartmental knee arthroplasty: fixed or mobile bearing?

Unicompartmental knee arthroplasty is an effective method for the treatment of medial compartment osteoarthritis. However, appropriate surgical tech- nique and optimum implant positioning are crucial for a satisfactory outcome. This study aimed to demonstrate the relation between the clinical scores and the alignment of the components in UKA.

Posteromedial Compartment Arthroscopy of the Knee and Resection of Osteophytes: An Anatomic Perspective on Posteromedial Knee Impingement.

Posteromedial knee pain is a common clinical problem. It is often accompanied by degenerative changes or tears in the posterior horn of the medial meniscus and/or pain during deep flexion of the knee. In more advanced cases, it is accompanied by the osteophytic formation of a cam lesion that develops gradually in the posterior of the medial condyle of the femur and, with it (or less frequently without it), an osteophytic lesion at the posterior of the tibia (i.

Segmental Medial Meniscus Transplantation in Combination With BMAC (Bone Marrow Aspirate Concentrate) Injection to Improve Healing and Prevent Extrusion.

In recent years, the lack of permanent protection of meniscus scaffold applications in partial and segmental loss of meniscus tissue and the low rates of long-term survival of meniscus transplantation have brought partial meniscus transplantation applications into question. This technique aims to accelerate the capsular healing and prevent future extrusion of the segmental piece by performing biological augmentation with bone marrow aspirate concentrate together with a stable fixation of the partial meniscus allograft.

Protection of the innervation of the tensor fasciae latae in hip direct anterior and anterolateral approaches: a cadaver study.

Purpose: This study aims to reveal the exact course of the superior gluteal nerve (SGN) branch innervating the tensor fascia lata (TFL) and show how it can be protected in the direct anterior approach (DAA) and anterolateral approach (ALA).

Methods: The anterolateral regions of 22 thighs from formalin-fixed cadavers were dissected. 3 anatomical points were determined.

Lateral Meniscus Allograft Transplantation in Combination with BMAC (Bone Marrow Aspirate Concentrate) Injection: Biologic Augmentation of the Allograft.

Meniscal allograft transplantation (MAT) has proven successful in relieving joint pain and providing functional improvement in patients who have undergone subtotal or total meniscectomy. Bone marrow aspirate concentrate (BMAC) is a biological adjuvant that was shown in the literature to be effective in treating cartilage damage and muscle-tendon tissue problems. The aim of the study is the concomitant use of MAT and BMAC, which are both considered biological treatments and would be beneficial in clinical practice.

A New Concept of Mosaicplasty: Autologous Osteoperiosteal Cylinder Graft Covered With Cellularized Scaffold.

A concern regarding osteochondral autograft transfer for chondral defects is donor-site morbidity of the knee, the most common source of the autograft. To avoid the drawbacks of osteochondral autograft transfer, a cylindrical osteoperiosteal graft harvested from the iliac crest covered by a same-sized cylinder of hyaluronic acid-based polymer scaffold pretreated with bone marrow aspirate concentrate and transferred to the chondral defect recipient site in the exact size for restoration of the subchondral bone and the articular cartilage.

Radiological Evaluation of Femoral Intercondylar Notch and Tibial Intercondylar Eminence Morphometries in Anterior Cruciate Ligament Pathologies Using Magnetic Resonance Imaging.

Purpose: To determine the relationship between femoral-tibial morphometries and anterior cruciate ligament (ACL) pathologies using magnetic resonance imaging (MRI).

Methods: We retrospectively evaluated 455 patients (211 females and 244 males) who underwent knee MRI with suspected ACL pathology. Imaging findings were classified as normal ACL ( = 119), degeneration of the ACL ( = 116), partial ACL tear ( = 103), and complete ACL tear ( = 117).

Role of FDG PET/CT in the Evaluation of Therapy Response in Systemic Juvenile Xanthogranuloma.

Juvenile xanthogranuloma, a rare type of non-Langerhans cell histiocytosis, is mostly seen in childhood and adolescence and generally manifests as widespread skin lesions. It rarely shows systemic involvement. Although the cutaneous form is often self-limited, systemic form is quite aggressive.

Renal Extramedullary Hematopoiesis Incidentally Detected on 18F-FDG PET/CT Imaging.

18F-FDG PET/CT imaging of a 68-year-old woman with a known clinical diagnosis of systemic lupus erythematosus and recent-onset ataxia revealed FDG-avid soft tissue masses in bilateral renal sinuses and mildly increased bone marrow activity. Consecutive tissue sampling with fine-needle biopsy from renal sinus masses confirmed mass-forming extramedullary hematopoiesis corresponding to FDG-avid soft tissue lesions. Here we present a rare case of bilateral mass-forming extramedullary hematopoiesis at renal sinuses incidentally detected on 18F-FDG PET/CT imaging.

The position of transarterial chemoembolization with drug-eluting beads and yttrium-90 transarterial radioembolization in patients with hepatocellular carcinoma: Consensus statements from a Delphi-method expert panel in Turkey.

Purpose: Clinical studies conducted in different geographic regions using different methods to compare transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) have demonstrated discordant results. Meta-analyses in this field indicate comparable overall survival (OS) with TACE and TARE, while reporting a longer time to progression and a higher downstaging effect with TARE treatment. In terms of isolated procedure costs, treatment with TARE is 2 to 3 times more, and in some countries even more, expensive than TACE.