Publications by authors named "Murano T"

An objective soft x-ray flat-field spectrograph employing a laminar-type bilayer coated, varied-line-spacing, spherical grating was designed to improve the detection limit and sensitivity of soft x-ray flat-field spectrographs in a region of 250-550 eV. As a design criterion, spectral flux, SF, [Hatano et al., Appl.

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Objectives: This study aimed to assess the effects of overseas assignments on the metabolic factors associated with lifestyle disease including body mass index, blood pressure, plasma glucose, lipid profiles, liver enzyme, and uric acid in Japanese individuals.

Methods: A retrospective cohort study was conducted using annual health examination data from employees of the Panasonic Corporation in Japan. We evaluated the differences in the changes in metabolic factors associated with lifestyle disease during the observation periods between the overseas and non-overseas assignment groups.

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Audience: Clerkship-level medical students, sub-interns, junior and senior residents, attending physicians.

Introduction: Bite injuries and envenomation are core content found in the model of the clinical practice of emergency medicine.1 However, depending on the geographic location of training or clinical practice, physicians may or may not be exposed to these pathologies.

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Article Synopsis
  • Regulatory changes have impacted the workload needed to manage graduate medical education (GME) programs, making it crucial to assess faculty efforts in emergency medicine (EM).
  • A survey study conducted from April 2022 to March 2023 involved 596 faculty members, who reported spending significant weekly hours on various GME activities, with program directors (PDs) dedicating the most time.
  • Significant differences in time spent on tasks were observed based on faculty roles and different quarters of the year, indicating a need for effective faculty support in residency programs.
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Background: Fecal immunochemical tests are commonly performed for colorectal cancer screening. Instant fecal occult blood measurement in toilet bowel movements would improve convenience. Hyperspectral imaging (HSI) enables the nondestructive evaluation of materials that are difficult to assess visually.

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Objectives: Few reports have detailed improvements in the quality of colonoscopies with continuous training post-fellowship completion. We examined the changes in colonoscopy performance among trainees during our advanced endoscopy training program.

Methods: Screening or surveillance colonoscopies performed by 11 trainees who participated in our 3-year advanced endoscopy training program between April 2015 and March 2020 were retrospectively analyzed.

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In submucosal invasive adenocarcinoma of the esophagogastric junction (pT1b-SM AEG), the extent of tumor submucosal (SM) invasion is measured using the vertical depth of SM invasion with the muscularis mucosa. This study aimed to investigate whether tumor thickness and depth of invasion without accounting for muscularis mucosa were superior to the vertical depth of SM invasion as metastasis predictors. We enrolled patients with pT1b-SM AEG who underwent endoscopic resection or surgical resection (SR) at our institution between January 2011 and September 2019 and were followed up for ≥2 years.

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Importance: In 2022, the US House of Representatives passed a bipartisan resolution (House of Representatives Resolution 1118 at the 117th Congress [2021-2022]) calling for meaningful nutrition education for medical trainees. This was prompted by increasing health care spending attributed to the growing prevalence of nutrition-related diseases and the substantial federal funding via Medicare that supports graduate medical education. In March 2023, medical education professional organizations agreed to identify nutrition competencies for medical education.

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Article Synopsis
  • Endoscopic resection (ER) is commonly used for early colorectal cancer, but the need for further surgery in cases of pathological T1 colorectal cancer (pT1CRC) is debated due to uncertain risks of lymph node metastasis (LNM).
  • This study analyzed 600 pT1CRC patients to explore the clinicopathological characteristics and LNM risk for those with lymphoid follicular replacement (LFR).
  • Findings revealed that 6.7% of patients had pT1CRC with LFR, and notably, none experienced LNM during a median follow-up of 61 months, suggesting that patients with LFR might not require additional surgical intervention even with deeper submucosal invasion.
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Article Synopsis
  • The study highlights the effectiveness of a noninvasive assay (Guardant Reveal) that detects circulating tumor DNA (ctDNA) in patients with resected colorectal cancer, which can predict recurrence without needing prior tissue tests.
  • Results showed that the assay provided sensitive and specific detection of minimal disease, with an impressive 81% sensitivity in later-stage colon cancer, and identified recurrences up to 5.3 months earlier than traditional methods.
  • The findings suggest that ctDNA testing could significantly enhance clinical management for stage II and higher colorectal cancer patients by offering a quicker and more accessible way to assess disease status.
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Multilayer diffraction gratings are designed to improve the detection limit and sensitivity of soft x-ray flat-field spectrographs in the region of 300-1000 eV, placing emphasis on Fe-L (705 eV), Cu-L (930 eV), and Zn-L (1012 eV) emissions. For this purpose, spectral flux was used as the performance index, which is proportional to the amount of optical flux incident into a detector and correlated with detection sensitivity. A super-mirror-type W/B4C multilayer coating [Koike et al.

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Objectives: Colonoscopy (CS) is an important screening method for the early detection and removal of precancerous lesions. The stool state during bowel preparation (BP) should be properly evaluated to perform CS with sufficient quality. This study aimed to develop a smartphone application (app) with an artificial intelligence (AI) model for stool state evaluation during BP and to investigate whether the use of the app could maintain an adequate quality of CS.

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Article Synopsis
  • * A randomized trial involved 901 patients undergoing endoscopies, where 3G-NBI showed a higher detection rate for GNs (7.3%) compared to TXI (5.0%) and WLI (5.6%).
  • * The findings suggest that 3G-NBI is superior in detecting GNs, leading to better outcomes, thereby highlighting its potential in clinical practices for early diagnosis.
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Background: Endoscopic submucosal dissection (ESD) can be performed for superficial esophageal cancer. However, performing ESD for superficial esophageal cancer on a previous endoscopic resection scar may be difficult.

Methods: We compared the outcomes between ESD for superficial esophageal cancers on previous endoscopic resection scar (group A) and that for naïve lesions (group B).

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This study proposes a simple evaluation method for deriving L-absorption information from two L-emission spectra of 3d transition metal (TM) elements obtained at two different accelerating voltages. This method realizes a spatial identity for X-ray emission and absorption spectroscopies. This method was evaluated for the Fe L-emission spectra of Fe and its oxides and was applied to the TM L-emission spectra of MnO, Co, CoO and NiO.

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Objectives: To describe formal remediation rates and processes in urology training programs nationally.

Design, Setting, And Participants: We performed a cross-sectional study by surveying program directors (PDs) through the Society of Academic Urologists. Formal remediation was defined as the process initiated when resident competency deficiencies were significant enough to necessitate documentation and notification of the Graduate Medical Education (GME) office.

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Article Synopsis
  • The study compares two bowel cleansing methods for colonoscopy preparation: Sodium picosulfate/magnesium citrate (SP/MC) and polyethylene glycol (PEG) with ascorbic acid, with a focus on patient acceptability and effectiveness.
  • The trial includes 540 participants aged 40-69 and evaluates bowel cleansing quality using the Boston Bowel Preparation Scale, along with other factors like patient satisfaction and detection of polyps.
  • Researchers aim to demonstrate that SP/MC is not only more acceptable due to its smaller dosage and better taste but also as effective as PEG for ensuring thorough bowel cleansing in outpatient settings.
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Laminar-type spherical diffraction gratings overcoated with carbon-based materials were designed, fabricated, and evaluated for the purpose of enhancing the analytical sensitivity of the flat-field spectrograph in a vacuum ultraviolet region of 35-110 eV. As the design benchmark for numerical calculations, diffraction efficiency (DE) and spectral flux, which are defined by the product of the DE and numerical aperture and correlate with the analytical sensitivity of the spectrograph, were used. To simplify the feasibility study on the overcoating effects, we assumed a laminar-type grating having a grating constant of 1/1000 mm and coated with a Au layer of 30.

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Background Away rotations allow emergency medicine (EM)-bound fourth-year medical students to experience a residency program's educational culture and influence the ranking of residency programs. The financial cost and geographic distance have limited student participation in away electives. In recent years, COVID-19 pandemic-related restrictions on away rotations resulted in the creation of multiple virtual courses.

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Article Synopsis
  • The study investigates the outcomes of endoscopic resection (ER) for submucosally invasive colorectal cancer (CRC) with a focus on vertical margin involvement and its implications for lymph node metastasis.
  • Researchers analyzed 395 cases from 2008 to 2020, finding that 21.5% had vertical incomplete ER, with significant rates of residual tumors and lymph node metastasis observed in this group.
  • The results emphasize the increased risks associated with vertical incomplete ER, highlighting the need for careful assessment and potential additional surgery to address residual tumors and lymph node involvement.
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Background: Narrative analysis and reflection have been found to support professional identity formation (PIF) and resilience among medical students. In the emergency department, students have used reflective practice to process challenging clinical experiences, such as ethical dilemmas or moral distress. An online discussion board, however, has not been described as a curricular component of emergency medicine (EM) rotations.

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Article Synopsis
  • Endoscopic resection (ER) using a bipolar snare shows promise in safely removing 10-15 mm colorectal lesions, with a focus on comparing outcomes with and without submucosal injection.
  • This study retrospectively analyzed 565 colorectal lesions from 463 patients, comparing hot snare polypectomy (HSP) and endoscopic mucosal resection (EMR) between January 2018 and June 2021.
  • Results indicated comparable resection rates (93.2% for HSP vs. 92.3% for EMR) and similar incidence of delayed bleeding, suggesting both methods are effective for lesion removal.
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