Timing of administration of antenatal magnesium sulphate and correlation with umbilical cord blood magnesium levels in preterm babies.

Background: The effectiveness of MgSO4 for foetal neuroprotection is acknowledged, but the best time to provide it in relation to birth is a conundrum, and dose schedule is yet unknown. Understanding the determinants of the magnesium levels in cord blood aids in determining the appropriate timing and length of administration.

Aim And Objective: To assess the cord blood magnesium concentration in relation to the timing of MgSO4 and delivery.

Elucidating the Effect of Antenatal Corticosteroids in the Late Preterm Period.

Aim And Objective: To determine the efficacy of antenatal corticosteroids given in the late preterm period.

Methodology: We conducted a retrospective case-control study on patients with singleton pregnancies who were at a risk of delivering in the late preterm period (34 weeks to 36 weeks 6 days). A total of 126 patients who had received antenatal corticosteroids (prenatal administration of either betamethasone or dexamethasone, minimum one dose) during the late preterm period were taken as cases, and 135 patients who had not received steroids antenatally due to various reasons, for example, who were clinically unstable, presented with active bleeding, non-reassuring foetal status that obligated an imminent delivery and those in active labour were included as controls.

spectroscopy: optical fiber probes for clinical applications.

Introduction: Fiber optic probe-based spectroscopy techniques are fast and highly objective methods for intraoperative diagnoses and minimally invasive surgical interventions for all procedures where endoscopic observations are carried out for cancers of different types. The Raman spectral features provide molecular fingerprint-type information and can reveal the subjects' pathological state in label-free manner, making endoscopy multiplexed fiber optic probe-based devices with the potential for translation from bench to bedside for routine applications.

Areas Covered: This review provides a general overview of different fiber-optic probes for measurements with emphasis on Raman spectroscopy for biomedical application.

Sonographic Estimation of the Fetal Head Circumference: Accuracy and Factors Affecting the Error.

Background: Sonographic measurement of fetal head circumference (HC) is an essential parameter for the estimation of fetal weight as well as in cases with abnormal fetal head size. Since there is a lack of data, the present study was to assess the accuracy of ultrasonographic estimation of fetal HC and to identify factors that affect the accuracy of fetal HC estimation.

Material And Methods: A prospective cohort observational study was conducted for a year.

A micro-Raman spectroscopy study of inflammatory condition of human cervix: Probing of tissues and blood plasma samples.

The present study explores the application of the micro-Raman spectroscopy technique to discriminate normal and cervicitis condition from cervical malignancy by analyzing the Raman signatures of tissues and plasma samples of the same subjects. The Raman peaks from tissue samples at 1026 cm,1298 cm and 1243 cm are attributed to glycogen, fatty acids and collagen and are found to be reliable signatures capable of identifying cervicitis and normal condition from cervical cancer. The Raman signatures from plasma samples belonging to carbohydrates (578 cm), lipids (1059 cm) and nucleic acids (1077 cm,1341 cm and 1357 cm) are quite useful to classify various pathological conditions of cervix at par with tissue based diagnosis.

Influence of transcutaneous electrical nerve stimulation on pain intensity and functional activities following lower segment cesarean section.

Background: Postoperative incisional pain following lower segment cesarean section (LSCS) is one of the commonly reported complaints which may affect mother-infant bonding, and restrict mobility and functional activities.

Purpose: To study the influence of transcutaneous electrical nerve stimulation (TENS) on pain intensity and functional activities using the Numerical Pain Rating Scale (NPRS) and the Patient Specific Functional Scale (PSFS) following LSCS from the postoperative day (POD) 1 to POD 4.

Methods: This quasi-experimental study consisted of 50 postpartum women who underwent LSCS and were assigned to an intervention group (IG) that received TENS and a control group (CG) that received routine hospital care.

We Need to Improve Prenatal Screening Practices in Primary Obstetric Care: A Representative Data from a Fetal Medicine Unit in Coastal Karnataka.

Background: The present observational data from the fetal medicine unit aim to identify gaps in prenatal screening modalities employed in the primary obstetric care population in coastal Karnataka.

Methods: A retrospective observational study of all referrals to Fetal Medicine unit is over 2 years. For each fetal abnormality, we reviewed the literature to note the range of gestational age at which the abnormality should almost always be diagnosed.

A Randomized Controlled Trial on the Efficacy of Integrated Yoga on Pregnancy Outcome.

Physiological and biochemical changes occur in pregnancy to nurture the developing fetus. Pregnancy-related experience is unique to every woman. Pregnancy symptoms and complications can range from mild to severe.

Blooming in the Hypothalamus.

Cavernomas are vascular malformations which are collections of endothelium-lined sinusoids without intervening cerebral parenchyma. Hypothalamic location of cavernoma is extremely rare. We present a case of a 34-year-old male who presented with complaints of recent memory loss and vomiting.

Occurrence of Synpolydactyly and Omphalocele in a Fetus with a Mutation.

Synpolydactyly (SPD) is an autosomal dominant congenital limb disorder due to mutations in . It is a phenotypically heterogeneous condition characterized by syndactyly of the third finger (F3), fourth finger (F4) and/or fourth toe (T4), and fifth toe (T5) with variably associated polydactyly. We report on a mother and fetus with SPD.

Osteoporosis Prevention and Management.

Osteoporosis, defined by BMD at the hip or lumbar spine that is less than or equal to 2.5 standard deviations below the mean BMD of a young-adult reference population, is the most common bone disease in humans affecting both sexes and all races. It's a silent killer affecting the quality of life due to fractures and postural changes.

Cystic Sertoli-Leydig Cell Tumour in a Postmenopausal Woman with Absent Virilising Symptoms: A Diagnostic Challenge.

A 60-year-old postmenopausal woman, presented with a left ovarian cystic mass with mildly elevated CA125 levels. An intraoperative frozen section showed oedematous ovarian stroma with interspersed large aggregates of spindle shaped stromal cells. Subsequently, the excised specimen was reported as Sertoli-Leydig Cell Tumour (SLCT) of intermediate differentiation.

Can Transabdominal Scan Predict a Short Cervix by Transvaginal Scan?

. To determine whether transabdominal screening can be used to screen women with short cervix on transvaginal scan. .

Quantifying proteinuria in hypertensive disorders of pregnancy.

Background. Progressive proteinuria indicates worsening of the condition in hypertensive disorders of pregnancy and hence its quantification guides clinician in decision making and treatment planning. Objective.

Neonatal sepsis, bacterial isolates and antibiotic susceptibility patterns among neonates.

Data from hospital records of 96 neonates hospitalised with sepsis were analysed using SPSS 11.5 version to identify sepsis--its signs and symptoms with which they were admitted, bacterial isolates and antibiotic susceptibility patterns among neonates admitted during 2007-2009. The retrospective data revealed that majority of the neonates 61 (63.

Premature ovarian aging in primary infertility: Triple X syndrome.

Genetic aberrations comprise one-third of women with premature ovarian aging (POA). X chromosome abnormalities are seen in these women. We report a case of a 29-year-old lady with primary infertility and POA.

Umbilical laparoscopic scar endometriosis.

Umbilical endometriosis is rare and challenging in both diagnosis and treatment. We report a case of an umbilical scar endometriotic nodule in a 39-year-old lady following laparoscopy-assisted vaginal hysterectomy. The wide local excision of the nodule and histopathological examination confirmed the diagnosis.

Prenatal diagnosis of congenital mesenchymal hamartoma of liver: a case report.

Hepatic mesenchymal hamartoma is a rare benign tumor. We present an unusual case of a fetal abdominal cyst, later diagnosed histopathologically to be mesenchymal hamartoma of liver. The organ of origin was indeterminate on both prenatal and postnatal ultrasounds.