Assessment of Treatment Outcomes with Complete Orthograde Obturation with Bioceramic Materials: A Scoping Review.

Aim: Bioceramic sealers are being used as obturation materials as they are known for hard tissue induction and facilitating periapical healing. Based on some studies, one can hypothesize that mineral trioxide aggregate (MTA) and biodentine used as the sole obturating material could reinforce the tooth and provide a better sealability than an MTA/biodentine apical plug with gutta-percha obturation. However, there are not many high-quality studies regarding outcomes of complete MTA/biodentine obturations compared with traditional obturation methods.

Antibiofilm efficiency of silver and copper nanoparticle incorporated calcium hydroxide as an intracanal medicament: An study.

Background And Objectives: Silver (Ag) and Copper (Cu) Nanoparticles (NP) are a potential substitute for disinfection during endodontic therapy because of their antibacterial action against an array of pathogens, including resistant strains. This study aimed to assess the antibiofilm efficiency of calcium hydroxide modified with Ag and Cu NP suspension against , using confocal laser scanning microscopy (CLSM) and colony forming units (CFU) analysis.

Methods: Dentine blocks were inoculated with Enterococcus faecalis for one week and 1 week-old biofilm of were randomly divided into 4 groups, control, calcium hydroxide, calcium hydroxide +2 % Cu NP and calcium hydroxide +2 % Ag NP.

An Evaluation of Sealability of Three Bioceramic Physical Variants in Coronal and Apical Thirds of Root Canals.

Aim: To assess the coronal and apical microleakage of mineral trioxide aggregate (MTA), Biodentine, and Bioceramic putty when used as coronal and apical seals in endodontically treated teeth.

Materials And Methods: The study was conducted on 90 mandibular premolar teeth. The groups were divided into two subgroups.

Pharmacotherapy for the Prevention of Depression and Behavioral Side Effects in Hematopoietic Stem Cell Transplantation Patients.

Depression and decreased quality of life (QoL) develop in approximately 30% of nondepressed hematopoietic stem cell transplantation (HSCT) recipients early after transplantation. To potentially prevent this complication, we conducted a prospective randomized trial to assess whether prophylaxis of nondepressed HSCT patients with the antidepressant sertraline (SER) in addition to supportive psychotherapy starting at admission for transplantation decreases the risk of depression and improves QoL. The primary objective of the study was to evaluate whether there was an added benefit of SER versus placebo along with routine supportive psychotherapy on the development of depression in patients receiving HSCT.

Analysis of RNA-Seq data using self-supervised learning for vital status prediction of colorectal cancer patients.

Background: RNA sequencing (RNA-Seq) is a technique that utilises the capabilities of next-generation sequencing to study a cellular transcriptome i.e., to determine the amount of RNA at a given time for a given biological sample.

Comparing Bacterial Leakage of Three Intraorifice Barrier Sealing Materials against and .

Aim: The purpose of this study was to evaluate the intraorifice sealing ability of light-cured glass-ionomer cement (LC-GIC), Tetric N-Flow, and ProRoot mineral trioxide aggregate (MTA) against and .

Materials And Methods: Crowns of the eighty human mandibular teeth were decapitated. Working length determination was performed, after which cleaning and shaping were carried out.

Evaluation of push-out bond strength of BioRoot RCS and AH Plus after using different irrigants: An study.

Aim: The aim of this study was to compare push-out bond strength of root canal spaces filled with AH-Plus and BioRoot RCS after using different irrigants.

Materials And Methods: Eighty single-rooted teeth were decoronated and endodontically treated by crown-down technique using ProTaper Universal rotary files progressively till F4 (40/0.06).

Experience Of Resident Presentations In Consultation-Liaison Psychiatry Grand Rounds: Increase Value For Clinical Education.

Background: Grand rounds is a formal meeting at which physicians and trainees discuss excellence in medical care. Residents should participate in scholarly activity per Accreditation Council for Graduate Medical Education (ACGME). Consultation-Liaison (CL) psychiatry focuses on caring for patients presenting with psychiatric complications in general hospital.

Gutta-percha in endodontics - A comprehensive review of material science.

The complete and three-dimensional fluid tight seal of the root canal system is the final component of the endodontic triad. The long-standing and closest material which has fulfilled this criterion is gutta-percha (GP). Several materials have been tried and tested as an endodontic filling material, of which GP has been most extensively used for years and has established itself as a gold standard.

Obstructive sleep apnea co-morbidity in patients with fibromyalgia: a single-center retrospective analysis and literature review.

Fibromyalgia (FM) is a chronic medical condition characterized by widespread pain, sleep disturbance, and cognitive dysfunction. Sleep disorders are thought to play a prominent role in the etiology and symptomatic management of FM, specifically obstructive sleep apnea (OSA). In order to provide collaborative care, we need a better understanding of any overlapping presentation of FM and OSA.

Review of mini-clinical evaluation exercise (mini-CEX) in a psychiatry clerkship.

Background: Direct observation of medical students with actual patients is important for the assessment of clinical skills including interviewing and counseling skills. This article describes medical students' experience of mini-clinical evaluation exercise (mini-CEX) during their clerkship in consultation psychiatry.

Materials And Methods: In our center during inpatient consultation psychiatry clerkship, all rotating students are expected to complete one mini-CEX assessment as part of their clinical training.

evaluation of efficacy of different rotary instrument systems for gutta percha removal during root canal retreatment.

Background: Complete removal of old filling material during root canal retreatment is fundamental for predictable cleaning and shaping of canal anatomy. Most of the retreatment methods tested in earlier studies have shown inability to achieve complete removal of root canal filling. Therefore the aim of this investigation was to assess the efficacy of three different rotary nickel titanium retreatment systems and Hedstrom files in removing filling material from root canals.

Dating of Acute and Subacute Subdural Haemorrhage: A Histo-Pathological Study.

Introduction: Microscopic study of the organization of the Subdural Haemorrhage (SDH) verified against the time period can help us in the determination of its age which has serious medico-legal implications. Very few studies concerning the dating of SDH are present in the literature.

Aim: This study was conducted for dating the early subdural haemorrhage by routine histopathological stains.

Molar Incisor Hypomineralization.

Molar incisor hypomineralization (MIH) is a developmental defect affecting teeth. High prevalence rates of MIH and its clinical implications are significant for both the patients and clinicians. A wide variation in defect prevalence (2.

Clinical, angiographic profile and percutaneous endovascular management of Takayasu's arteritis - A single centre experience.

Objective: Aim of the study was to evaluate clinical, angiographic profile and percutaneous endovascular management of Takayasu's arteritis.

Background: Takayasu's arteritis is a chronic inflammatory vasculitis affecting the aorta and its major branches. Although it is more prevalent in Asia, the distribution of the disease is worldwide with different vascular involvement patterns and clinical manifestations.

Dating of Early Subdural Haematoma: A Correlative Clinico-Radiological Study.

Introduction: Determination of post-traumatic interval remains one of the foremost important goals of any forensic investigation related to human crimes. The estimation of time since injury in cases of subdural haemorrhage has been studied only by a few investigators on the histological and radiological front.

Aim: The purpose of this study was to determine the post-traumatic interval of Subdural Haemorrhage (SDH) based on Hounsfield Unit measurements (HU) on Computed Tomography (CT) in surviving victims of head injury.

Intrauterine Fetal Death in Gunshot Injury to the Gravid Uterus: Forensic Perspective.

Assault on pregnant women is not a rare event; however forensic analysis of gunshot injuries among the same group requires a greater deliberation. This is the report of a 38-week-old fetus which succumbed following gunshot injuries to the mother while the latter survived. The uniqueness of fetal injuries in the form of avulsed wound with complete detachment of anus is of great forensic interest.

Why Does Mutual-Information Work for Image Registration? A Deterministic Explanation.

This paper proposes a deterministic explanation for mutual-information-based image registration (MI registration). The explanation is that MI registration works because it aligns certain image partitions. This notion of aligning partitions is new, and is shown to be related to Schur- and quasi-convexity.

Directly reconstructing principal components of heterogeneous particles from cryo-EM images.

Structural heterogeneity of particles can be investigated by their three-dimensional principal components. This paper addresses the question of whether, and with what algorithm, the three-dimensional principal components can be directly recovered from cryo-EM images. The first part of the paper extends the Fourier slice theorem to covariance functions showing that the three-dimensional covariance, and hence the principal components, of a heterogeneous particle can indeed be recovered from two-dimensional cryo-EM images.

Depression in the US population during the time periods surrounding the great recession.

Objective: To determine whether the time periods surrounding the 2008 US economic downturn were accompanied by an increase in prevalence of depression in the US adult population.

Method: We used data from the 24,182 adults aged ≥ 18 years who participated in the National Health and Nutrition Examination Survey during 2005-2012. A cross-sectional analysis was performed at each time period to determine prevalence of major and other depression as assessed by standardized questionnaires based on 9 criteria for major depressive episodes defined by DSM-IV.

Shared neurobiological pathways between type 2 diabetes and depressive symptoms: a review of morphological and neurocognitive findings.

Type 2 diabetes (T2D) patients are twice as likely to experience depressive symptoms than people without T2D, resulting in greater economic burden, worse clinical outcomes, and reduced quality of life. Several overlapping pathophysiological processes including hypothalamic-pituitary-adrenal axis hyperactivity, sympathetic nervous system activation, and elevated pro-inflammatory biomarkers are recognized as playing a role between T2D and depressive symptoms. However, other neurobiological mechanisms that may help to further link these comorbidities have not been extensively reviewed.

Rehabilitation of complicated crown-root fracture by fragment reattachment and intraradicular splinting: case reports.

This paper describes the rehabilitation of two traumatised teeth in two patients namely; A maxillary left central incisor with a relatively rare combination of multiple fractures- uncomplicated crown fracture, complicated crown-root fracture along with an oblique fracture in middle third of the root and A traumatised mandibular central incisor with a horizontal fracture in cervical third of the root and complete separation of the fragments. In both cases, initially the fractured crown fragments were extracted which was followed by pulpectomy and placement of fiber posts luted with resin cement. The fractured fragments were then reattached to the respective teeth using resin cement.

Comparative evaluation of the antibacterial effects of four dentine bonding systems: An in vitro study.

Aim: The aim of this in vitro study was to evaluate and the compare antibacterial efficacy of four dentin bonding system against Streptococcus mutans, Streptococcus salivarius and Lactobacillus acidophilus over a period of three months using agar disk diffusion test.

Methodology: All the three standard bacterial strains were inoculated into BHI broth and incubated at 37°C for 48 hours. A 100 μl of broth suspension containing aliquots of S.