Business-as-usual trends will largely miss 2030 global conservation targets.

To address climate change and global biodiversity loss, the world must hit three important international conservation targets by 2030: protect 30% of terrestrial and marine areas, halt and reverse forest loss, and restore 350 Mha of degraded and deforested landscapes. Here, we (1) provide estimates of the gaps between these globally agreed targets and business-as-usual trends; (2) identify examples of rapid past trend-shifts towards achieving the targets; and (3) link these past trend-shifts to different levers. Our results suggest that under a business-as-usual scenario, the world will fail to achieve all three targets.

Diverse values of nature for sustainability.

Twenty-five years since foundational publications on valuing ecosystem services for human well-being, addressing the global biodiversity crisis still implies confronting barriers to incorporating nature's diverse values into decision-making. These barriers include powerful interests supported by current norms and legal rules such as property rights, which determine whose values and which values of nature are acted on. A better understanding of how and why nature is (under)valued is more urgent than ever.

[Micronuclear and antitumor activities of two newly synthesized pyrimidine derivatives].

Micronuclear and antitumor activities of two newly synthesized iodides of pyrazolo[1,5a]pyrimidines were investigated using mice model. It has been shown that both compounds are slightly toxic and have no antitumor activity in mice with Ehrlich's ascites carcinoma. Only one of them has weak micronuclear activity.

Effect of Andrographis paniculata extract on progesterone in blood plasma of pregnant rats.

The effect of the powdered extract of Andrographis paniculata leaves (APE), an active principle of Kan Jang tablets [standardized for content of andrographolide (4.6%) and 14-deoxo-andrographolide (2.3%) content (total andrographolids--6.

Energy consumption of termite colonies of Nasutitermes ephratae (Isoptera: Termitidae).

Measurements of CO2 production of whole termite colonies showed that respiration intensity varies slightly during the daily cycle, that the relation between standard metabolism and colony size is best described with a negative exponential, taking into account the proportion of the various castes. Larger colonies were more efficient in their energy use, suggesting that energetic considerations may contribute in explaining the maintenance in evolution of complex societies.

[Rehabilitation of patients following the implantation of an anti-embolism cava filter].

The article analyses the efficacy of rehabilitation measures after implantation of a REPTELA cava-filter in 750 patients in the immediate postimplantation period and in 400 patients in late-term periods of up to 8 years. The average duration of the hospital stage of rehabilitation was 45 days for patients with thromboembolism of the pulmonary artery and 22 days for those without this condition. The application of a complex of rehabilitation measures makes it possible to restore the working capacity of 78.

[State of the ileocaval segment after implantation of the REPTEL antiembolic cava filter].

The condition of the inferior vena cava system was studied in 597 patients after percutaneous implantation of the antiembolic cava-filter on the basis of the clinical findings and results of angiographic and pathoanatomical examination. The patency of the inferior vena cava was found to be maintained in the immediate postimplantation period in most patients. The causes of occlusion of the inferior vena cava in 10% of cases (according to the clinical findings) were embolic occlusion of the cava-filter and ascending thrombosis of the iliocaval segment.

[Prevention of pulmonary thromboembolism by percutaneous implantation of REPTELA vena cava-filter].

Experience in clinical application of the new antiembolic REPTELA cava-filter is generalized. The immediate (750 patients) and late-term results (400 patients) of implantation of the filter are discussed. Thromboembolism of the pulmonary artery was encountered in the postimplantation period in 1.

[Complications after implantation of anti-embolic cava filter].

The article is based on study of the immediate results of REPTELA cava-filter implantation in 750 patients and the late-term results in 400 patients. The incidence of the complications is low. Hematoma at the site of subclavian vein puncture developed in 1.

[Assessment of the results of implantation of an anti-embolic cava-filter using the method of ultrasonic scanning].

By the method of ultrasound scanning, 56 patients were examined at the early and 115 patients at the late period after the percutaneous implantation of a cava-filter. Ultrasound scanning was performed in the cross and longitudinal section planes. In 28 patients, the embolic occlusion of the cava-filter was revealed, in 19-thrombosis of infrarenal inferior vena cava (IVC).

[Study of the potential carcinogenic activity of reserpine].

A single dose of 2.5 mg/kg body of reserpine was injected subcutaneously (once a week) or given per os (2-5 times a week) to 100 rats and 100 mice of local breeding throughout their life-time. Another 100 rats and 100 mice in control received only sunflower oil used as a vehicle.

[Experimental study of the carcinogenicity of phenacetin].

150 rats and 100 mice were treated subcutaneously (once weekly) and orally (2-5 times a week) with single doses of phenacetin (300-1,000 mg/kg and 800 mg/kg suspended in sunflower oil, respectively). 100 rats and 100 mice in control received sunflower oil alone. Tumor incidence in rats after subcutaneous treatment was 14% and 20%--after oral treatment; in control rats--5 and 5.