Marine-Derived Furanones Targeting Quorum-Sensing Receptors in : Molecular Insights and Potential Mechanisms of Inhibition.

The quorum-sensing (QS) machinery in disease-causing microorganisms is critical in developing antibiotic resistance. In , QS is involved in biofilm formation, virulence factors production, and general tolerance to antimicrobials. Owing to the major role QS plays, interference in the process is probably a facile route to overcome antimicrobial resistance.